Thomadsen Bruce R, Erickson Beth A, Eifel Patricia J, Hsu I-Chow, Patel Rakesh R, Petereit Daniel G, Fraass Benedick A, Rivard Mark J
Department of Medical Physics, University of Wisconsin, Madison, Wisconsin.
Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Pract Radiat Oncol. 2014 Mar-Apr;4(2):65-70. doi: 10.1016/j.prro.2013.12.005. Epub 2014 Feb 5.
This white paper was commissioned by the American Society for Radiation Oncology (ASTRO) Board of Directors to evaluate the status of safety and practice guidance for high-dose-rate (HDR) brachytherapy. Given the maturity of HDR brachytherapy technology, this white paper considers, from a safety point of view, the adequacy of general physics and quality assurance guidance, as well as clinical guidance documents available for the most common treatment sites. The rate of medical events in HDR brachytherapy procedures in the United States in 2009 and 2010 was 0.02%, corresponding to 5-sigma performance. The events were not due to lack of guidance documents but failures to follow those recommendations or human failures in the performance of tasks. The white paper summarized by this Executive Summary reviews current guidance documents and offers recommendations regarding their application to delivery of HDR brachytherapy. It also suggests topics where additional research and guidance is needed.
本白皮书由美国放射肿瘤学会（ASTRO）董事会委托撰写，旨在评估高剂量率（HDR）近距离放射治疗的安全状况及实践指南。鉴于HDR近距离放射治疗技术已成熟，本白皮书从安全角度出发，考量了一般物理和质量保证指南的充分性，以及针对最常见治疗部位的临床指南文件。2009年和2010年美国HDR近距离放射治疗程序中的医疗事件发生率为0.02%，相当于5西格玛性能。这些事件并非由于缺乏指导文件所致，而是未能遵循这些建议或执行任务时出现人为失误。本执行摘要总结的白皮书回顾了当前的指导文件，并就其在HDR近距离放射治疗实施中的应用提出建议。它还指出了需要进一步研究和指导的主题。
