通过国际原子能机构全球近距离放射治疗计划解决宫颈癌负担。
Addressing the burden of cervical cancer through IAEA global brachytherapy initiatives.
机构信息
Applied Radiation Biology and Radiotherapy Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria; Department of Radiation Oncology, NCI Cairo University, Cairo, Egypt; Department of Radiation Oncology, Hiroshima University, Hiroshima, Japan.
Department of Radiation Oncology, University of Pennsylvania, Pennsylvania; Oncology Program, University of Botswana and Botswana-University of Pennsylvania Partnership, Gaborone, Botswana.
出版信息
Brachytherapy. 2020 Nov-Dec;19(6):850-856. doi: 10.1016/j.brachy.2020.07.015. Epub 2020 Sep 11.
PURPOSE
Brachytherapy (BT) is an essential component of definitive therapy for locally advanced cervical cancer. Despite the advantages of the dose distribution with BT in cervical cancer, there is paucity of specific skills required for good-quality BT applications. Furthermore, replacing BT with other modern external beam techniques as a boost can lead to suboptimal results in cervix cancer.
METHODS AND MATERIALS
Review of available IAEA resources, research and cooperation programs available from the IAEA was completed. These opportunities can be used to address challenges in Brachytherapy. The International Atomic Energy Agency (IAEA) provides support for BT through various means that includes education and training, both long term, short term and continuing medical education of professionals, providing expert visits to support implementation, development of curricula for professionals, e-learning through the human health campus, contouring workshops, 2D to 3D BT training, and virtual tumor boards. In addition, the IAEA provides support for implementing quality assurance in radiotherapy to its member states and provides guidelines for comprehensive audits in radiation therapy (QUATRO), and produces safety standards and training in radiation safety. In addition, mapping BT resources, making the case for investment and support for setting up BT services and radiotherapy centers are also available. The IAEA Dosimetry Laboratory provides calibration services to Secondary Standards Dosimetry Laboratories for well chambers used to confirm the reference air kerma rate of Co60 and Ir192 high-dose-rate BT sources, as well as for Cs137 low-dose-rate sources. Furthermore, the IAEA supports research and development in radiotherapy (and BT) through coordinated research activities that include controlled randomized clinical trials, Patterns of Care studies among others. Partnerships with professional organizations and funding bodies, as well as through the United Nations Joint Global Programme on Cervical Cancer Prevention and Control support radiotherapy activities, including BT in countries worldwide.
CONCLUSION
The IAEA supports brachytherapy implementation, training and research and provides resources to professionals in the area.
目的
近距离放射治疗（Brachytherapy，BT）是局部晚期宫颈癌根治性治疗的重要组成部分。尽管 BT 在宫颈癌中的剂量分布具有优势，但对于高质量 BT 应用所需的特定技能却知之甚少。此外，用其他现代外照射技术替代 BT 作为增敏剂，可能会导致宫颈癌的治疗效果不理想。
方法和材料
对国际原子能机构（IAEA）现有的资源、研究和合作计划进行了回顾。这些机会可用于解决 BT 中的挑战。国际原子能机构（IAEA）通过多种方式为 BT 提供支持，包括对专业人员进行教育和培训（包括长期、短期和继续医学教育），为实施提供专家访问支持、为专业人员制定课程、通过人类健康园区进行电子学习、勾画研讨会、2D 到 3D BT 培训以及虚拟肿瘤委员会。此外，IAEA 还为成员国实施放射治疗质量保证提供支持，并提供放射治疗全面审核（QUATRO）指南，以及辐射安全标准和培训。此外，还可以对 BT 资源进行映射，为投资和支持建立 BT 服务和放射治疗中心提出建议。IAEA 剂量学实验室为次级标准剂量学实验室提供校准服务，用于确认 Co60 和 Ir192 高剂量率 BT 源的参考空气比释动能率以及 Cs137 低剂量率源的参考空气比释动能率的井型室。此外，IAEA 通过协调研究活动，包括对照随机临床试验、护理模式研究等，支持放射治疗（包括 BT）的研究与开发。与专业组织和资助机构建立伙伴关系，并通过联合国全球宫颈癌预防和控制联合方案，支持包括 BT 在内的全球各国的放射治疗活动。
结论
IAEA 支持 BT 的实施、培训和研究，并为该领域的专业人员提供资源。
Zotero 插件