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脑成星形细胞瘤:一种放射病理学诊断。

Cerebral astroblastoma: A radiopathological diagnosis.

作者信息

Singh Deepak Kumar, Singh Neha, Singh Ragini, Husain Nuzhat

机构信息

Department of Neurosurgery, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.

Department of Radiodiagnosis, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

J Pediatr Neurosci. 2014 Jan;9(1):45-7. doi: 10.4103/1817-1745.131485.

Abstract

Astroblastoma is a rare glial neoplasm whose histogenesis has been clarified recently. It primarily occurs in children and young adults. We are reporting a case of 12-year-old girl child who presented with features of raised intracranial tension and generalized tonic-clonic seizures. Brain magnetic resonance imaging revealed a large well-circumscribed, cystic lesion without perifocal edema, and enhancing mural nodule in right parietal region. A radiological differential diagnosis of pilocytic astrocytoma and cerebral astroblastoma was made. A complete excision was done and histologically the lesion turned out to be an astroblastoma. We review the histology, immunohistochemistry, and imaging features of astroblastoma and survey the current literature, treatment strategies, and prognostic aspects for the management of this rare neoplasm.

摘要

成星形细胞瘤是一种罕见的神经胶质肿瘤,其组织发生学最近已得到阐明。它主要发生于儿童和青年成人。我们报告一例12岁女童,其表现为颅内压升高和全身性强直阵挛发作。脑磁共振成像显示右顶叶区域有一个边界清晰的大囊性病变,无灶周水肿,并有强化的壁结节。做出了毛细胞型星形细胞瘤和脑成星形细胞瘤的放射学鉴别诊断。进行了完整切除,组织学检查结果显示该病变为成星形细胞瘤。我们回顾了成星形细胞瘤的组织学、免疫组织化学和影像学特征,并查阅了当前关于这种罕见肿瘤的治疗策略和预后方面的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dc0/4040033/f0a325d45e27/JPN-9-45-g001.jpg

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