Rana Abdul Qayyum, Böke Bilun Naz, Qureshi Abdul-Rehman M, Rana Mohammad A, Rahman Maniza
1Parkinson's Clinic of Eastern Toronto & Movement Disorders Centre, Parkinson's Disease and Movement Disorder Centre, Toronto, ON, Canada.
Int J Neurosci. 2015 Apr;125(4):253-5. doi: 10.3109/00207454.2014.929128. Epub 2014 Jun 25.
Essential tremor (ET) and Parkinson's disease (PD) tremor differ in type, frequency and distribution. Despite being two separate disorders, there have been cases reported of comorbidity for ET-PD. Studies have reported an increase in the incidence of ET in relatives of patients with PD, yet the risk of developing PD in ET patients has not been thoroughly investigated. Our study set out to determine the incidence of precedent ET in PD patients. We conducted a retrospective chart review analysis of 332 idiopathic PD patients to determine how many of them had ET prior to the diagnosis of PD and the percentage of them who were also diagnosed with ET. Our results indicate that the prevalence of precedent ET among a population of idiopathic PD patients was not any higher than the prevalence of ET in a comparable general population. Our results support the notion that ET and PD are mutually independent disorders. Further studies are needed to understand the exact relationship between these two disorders.
特发性震颤(ET)和帕金森病(PD)的震颤在类型、频率和分布上有所不同。尽管是两种不同的疾病,但已有ET-PD共病的病例报告。研究报告称,PD患者亲属中ET的发病率有所增加,然而ET患者患PD的风险尚未得到充分研究。我们的研究旨在确定PD患者中既往ET的发病率。我们对332例特发性PD患者进行了回顾性病历审查分析,以确定其中有多少人在PD诊断之前患有ET,以及同时被诊断为ET的患者百分比。我们的结果表明,特发性PD患者群体中既往ET的患病率并不高于可比的普通人群中ET的患病率。我们的结果支持ET和PD是相互独立的疾病这一观点。需要进一步研究以了解这两种疾病之间的确切关系。