Rosenthal Amir, Kellnberger Stephan, Omar Murad, Razansky Daniel, Ntziachristos Vasilis
Institute for Biological and Medical Imaging (IBMI), Technical University of Munich and Helmholtz Center Munich;
Institute for Biological and Medical Imaging (IBMI), Technical University of Munich and Helmholtz Center Munich.
J Vis Exp. 2014 May 11(87):50847. doi: 10.3791/50847.
Optical sensors of ultrasound are a promising alternative to piezoelectric techniques, as has been recently demonstrated in the field of optoacoustic imaging. In medical applications, one of the major limitations of optical sensing technology is its susceptibility to environmental conditions, e.g. changes in pressure and temperature, which may saturate the detection. Additionally, the clinical environment often imposes stringent limits on the size and robustness of the sensor. In this work, the combination of pulse interferometry and fiber-based optical sensing is demonstrated for ultrasound detection. Pulse interferometry enables robust performance of the readout system in the presence of rapid variations in the environmental conditions, whereas the use of all-fiber technology leads to a mechanically flexible sensing element compatible with highly demanding medical applications such as intravascular imaging. In order to achieve a short sensor length, a pi-phase-shifted fiber Bragg grating is used, which acts as a resonator trapping light over an effective length of 350 µm. To enable high bandwidth, the sensor is used for sideway detection of ultrasound, which is highly beneficial in circumferential imaging geometries such as intravascular imaging. An optoacoustic imaging setup is used to determine the response of the sensor for acoustic point sources at different positions.
超声光学传感器是压电技术的一种很有前景的替代方案,这一点最近在光声成像领域得到了证明。在医学应用中,光学传感技术的一个主要局限在于其易受环境条件影响,例如压力和温度的变化,这可能会使检测饱和。此外,临床环境常常对传感器的尺寸和坚固性有严格限制。在这项工作中,展示了脉冲干涉测量法与基于光纤的光学传感相结合用于超声检测。脉冲干涉测量法能使读出系统在环境条件快速变化的情况下具备稳健性能,而全光纤技术的使用则带来了一个机械上灵活的传感元件,该元件与诸如血管内成像等要求极高的医学应用兼容。为了实现较短的传感器长度,使用了一个π相移光纤布拉格光栅,它作为一个谐振器,在350微米的有效长度上捕获光。为了实现高带宽,该传感器用于超声的侧向检测,这在诸如血管内成像的圆周成像几何结构中非常有利。使用一个光声成像装置来确定传感器对不同位置的声学点源的响应。