对 PPO 底物识别机制的深入了解：迈向有效抑制剂的合理设计。
Mechanistic insights into the substrate recognition of PPO: toward the rational design of effective inhibitors.
机构信息
Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan 430079, P.R. China.
出版信息
Future Med Chem. 2014 Apr;6(6):597-9. doi: 10.4155/fmc.14.29.
Abstract
“…the obtained structural and energetic insights of the substrate recognition process represent a paradigm shift and a new starting point for structure-based design of novel, more potent PPO inhibitors.”
摘要
“......所得出的底物识别过程的结构和能量见解代表了一种范式转变，为新型、更有效的 PPO 抑制剂的基于结构的设计提供了一个新的起点。”
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