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宫内死胎引产的临床管理:剖宫产发生率及相关情况评估

Clinical management of the induction of labor in intrauterine fetal death: evaluation of incidence of cesarean section and related conditions.

作者信息

do Nascimento Maria Isabel, Cunha Alfredo de Almeida, Oliveira Sandra Regina dos Santos Muri

机构信息

Departamento de Epidemiologia e Bioestatística, Universidade Federal Fluminense, Niterói, RJ, Brasil.

Departamento de Ginecologia e Obstetrícia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

出版信息

Rev Bras Epidemiol. 2014 Jan-Mar;17(1):203-16. doi: 10.1590/1415-790x201400010016eng.

Abstract

OBJECTIVE

To assess the incidence and conditions associated with cesarean section in a cohort of pregnant women with intrauterine fetal death (IUFD), and clinical management to anticipate the childbirth.

METHODS

It was a retrospective cohort study with 163 mothers with IUFD, at the second half of pregnancy, who were managed to anticipate childbirth using pharmacological preparations and/or a mechanical method (Foley catheter) in a teaching hospital in Rio de Janeiro State, Brazil. Cox regression was used to evaluate the effect of the clinical methods on the kind of delivery.

RESULTS

The Subgroups A (misoprostol or Oxytocin), B (misoprostol and Oxytocin), and C (Foley catheter alone or combined with misoprostol and/or Oxytocin) were formed according to the applied methods. Nine out of 163 cases ended with cesarean section. The incidence of cesarean section was 3.5 per 1,000 people-hours, meaning that a pregnant woman with IUFD had a 15.6% risk of cesarean section during the first 48 hours of clinical management to anticipate childbirth. The conditions significantly associated with the mode of delivery were placental abruption (HR: 44.97), having two or more previous cesarean deliveries (HR: 10.03), and mechanical method with Foley catheter (HR: 5.01).

CONCLUSION

Cesarean section was an essential conduct in this cohort and followed previous cesarean delivery and placental abruption. The effect of the mechanical method on the abdominal route suggests that the Foley catheter method was used in the most difficult cases and that the surgery was performed to ensure maternal health.

摘要

目的

评估一组宫内死胎(IUFD)孕妇剖宫产的发生率及相关情况,以及预测分娩的临床管理措施。

方法

这是一项回顾性队列研究,研究对象为163名妊娠晚期发生IUFD的母亲,她们在巴西里约热内卢州的一家教学医院接受了使用药物制剂和/或机械方法(Foley导管)预测分娩的管理。采用Cox回归评估临床方法对分娩方式的影响。

结果

根据应用方法形成了A组(米索前列醇或缩宫素)、B组(米索前列醇和缩宫素)和C组(单独使用Foley导管或与米索前列醇和/或缩宫素联合使用)。163例中有9例以剖宫产结束。剖宫产发生率为每1000人时3.5例,这意味着IUFD孕妇在预测分娩的临床管理的前48小时内剖宫产风险为15.6%。与分娩方式显著相关的情况是胎盘早剥(风险比:44.97)、既往有两次或更多次剖宫产史(风险比:10.03)以及使用Foley导管的机械方法(风险比:5.01)。

结论

剖宫产在该队列中是必要的操作,且与既往剖宫产和胎盘早剥有关。机械方法对腹部途径的影响表明,Foley导管方法用于最困难的病例,且进行手术是为了确保产妇健康。

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