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结局为胎儿死亡的妊娠存在更高的产科护理延误风险:一项病例对照研究。

Pregnancies with an outcome of fetal death present higher risk of delays in obstetric care: A case-control study.

机构信息

Department of Community Health, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Department of Maternal and Child Health, Federal University of Ceará, Fortaleza, Ceará, Brazil.

出版信息

PLoS One. 2019 Apr 29;14(4):e0216037. doi: 10.1371/journal.pone.0216037. eCollection 2019.

Abstract

The objective of this study was identify the association between delays in the care provided to pregnant women and the fetal death outcome, in a tertiary reference maternity hospital in the Northeastern Brazil. A case-control study, with 72 cases of fetal death and 144 controls (live births) in women admitted to the Obstetrics Service of the Assis Chateaubriand Teaching Maternity Hospital, in Fortaleza, Ceará. Controls were matched (2:1) by the approximate gestational age of the case. The groups were compared using the three delays model of obstetric care. The Pearson's Chi-square test and the Fisher's exact test were used to compare the groups. P <0.05 was considered statistically significant. The Group with fetal death had a smaller number of prenatal consultations (> 6 consultations: 27.8% in cases, 40.3% in controls, p = 0.003), less risk classification of pregnancy (41.7% vs 55.9%, p = 0.048), less guidance about the health facility for delivery (44.5% vs 64%, p = 0.009), lower frequency of cesarean sections (25.4% vs 65.7%) and higher frequency of hemorrhagic syndromes (33.3% vs 19.4%, p = 0.024) and syphilis (15.3% vs 4.2%, p = 0·004). Variables that persisted significantly associated with fetal death in the logistic regression were: Refusal of assistance (OR = 4.07, IC 95%: 1.08-15.3), Absence or inadequacy of prenatal care (OR = 2.69, IC 95%: 1.07-6.75), Delay in diagnosis (OR = 10.3, IC 95%: 2.58-41.4) and Inadequate patient conduct (OR = 4.88; IC 95%: 1.43-16.6). Despite of having a higher frequency of obstetric complications, gestations with fetal death are more prone to delays in obstetric care.

摘要

本研究旨在探讨在巴西东北部的一家三级参考产科医院,孕妇医疗延误与胎儿死亡结局之间的关联。采用病例对照研究,共纳入 72 例胎儿死亡病例和 144 例对照(活产),均为在福塔雷萨的 Assis Chateaubriand 教学产科医院接受产科服务的孕妇。对照(活产)按照病例的大致胎龄进行 2:1 匹配。使用产科保健的三个延迟模型对两组进行比较。使用 Pearson's Chi-square 检验和 Fisher's exact 检验比较两组。P<0.05 被认为具有统计学意义。胎儿死亡组的产前检查次数较少(>6 次:27.8%的病例,40.3%的对照,p=0.003),妊娠风险分类较低(41.7%对 55.9%,p=0.048),分娩时选择医疗机构的指导较少(44.5%对 64%,p=0.009),剖宫产率较低(25.4%对 65.7%),出血性综合征发生率较高(33.3%对 19.4%,p=0.024)和梅毒发生率较高(15.3%对 4.2%,p=0.004)。多因素逻辑回归分析显示,与胎儿死亡显著相关的变量包括:拒绝接受援助(OR=4.07,95%CI:1.08-15.3)、产前保健不足或缺失(OR=2.69,95%CI:1.07-6.75)、诊断延迟(OR=10.3,95%CI:2.58-41.4)和患者管理不当(OR=4.88;95%CI:1.43-16.6)。尽管胎儿死亡组的产科并发症发生率较高,但更易发生产科保健延误。

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