Yamagishi A, Onodera T, Ishikawa S, Furukawa K, Nemoto F, Itoh S, Ishibashi K, Nawa T
Nihon Hotetsu Shika Gakkai Zasshi. 1989 Oct;33(5):1194-201. doi: 10.2186/jjps.33.1194.
The purpose of this study is to investigate the relationship between gingival discoloration and Ag2S. Minute granules of dental alloys were embedded in the gingiva during a 5-11 months span, and their histological and colorimetric analyses were undertaken. Results showed the following; 1. Cases of low melting silver alloy, 12% Au-Ag-Pd alloy, and Ni-Cr alloy all resulted in gingival discoloration, but it did not occur during the specified experimental period. 2. Regardless of the size of the granules or time, the electron microanalyser showed no signs of sulfer detection in cases of low melting silver alloy. However, in the case of 12% Au-Ag-Pd alloy, sulfer was detected 5 months later for only those granules having the size of 0.2-0.3 microns. No sulfer was detected in cases of Ni-Cr alloy. 3. Although no proliferation of inflammatory cells were observed around those areas surrounding the 12% Au-Ag-Pd alloy granules, they appeared in cases of the low melting silver alloy and Ni-Cr alloy.
本研究的目的是调查牙龈变色与硫化银之间的关系。在5至11个月的时间段内，将牙科合金的微小颗粒植入牙龈，并进行组织学和比色分析。结果如下：1. 低熔点银合金、12%金-银-钯合金和镍铬合金病例均导致牙龈变色，但在规定的实验期内未出现。2. 无论颗粒大小或时间如何，电子微分析仪在低熔点银合金病例中均未显示出硫的检测迹象。然而，在12%金-银-钯合金的情况下，仅在那些尺寸为0.2至0.3微米的颗粒中，5个月后检测到了硫。在镍铬合金病例中未检测到硫。3. 虽然在12%金-银-钯合金颗粒周围的区域未观察到炎症细胞增殖，但在低熔点银合金和镍铬合金病例中出现了炎症细胞增殖。
