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采用股四头肌保留股薄肌下入路和内侧髌旁入路进行初次全膝关节置换术后的早期患者结局:一项随机双盲临床试验

Early Patient Outcomes After Primary Total Knee Arthroplasty with Quadriceps-Sparing Subvastus and Medial Parapatellar Techniques: A Randomized, Double-Blind Clinical Trial.

作者信息

Tomek Ivan M, Kantor Stephen R, Cori LuAnne A, Scoville Jennifer M, Grove Margaret R, Morgan Tamara S, Swarup Ishaan, Moschetti Wayne E, Spratt Kevin F

机构信息

Geisel School of Medicine at Dartmouth, 1 Rope Ferry Road, Hanover, NH 03755. E-mail address for T.S. Morgan:

出版信息

J Bone Joint Surg Am. 2014 Jun 4;96(11):907-915. doi: 10.2106/JBJS.L.01578.

Abstract

BACKGROUND

Techniques that reduce injury to the knee extensor mechanism may cause less pain and allow faster recovery of knee function after primary total knee arthroplasty. A quadriceps-sparing (QS) subvastus technique of total knee arthroplasty was compared with medial parapatellar arthrotomy (MPPA) to determine which surgical technique led to better patient-reported function and less postoperative pain and opioid utilization.

METHODS

In this prospective, double-blind study, 129 patients undergoing total knee arthroplasty were randomized to the QS or the MPPA group after skin incision. All surgical procedures utilized minimally invasive surgery principles and standardized anesthesia, implants, analgesia, and rehabilitation. The Knee Society Score (KSS) was obtained at baseline and one and three months after surgery. Weekly telephone interviews were used to collect patient-reported outcomes including ambulatory device use, the UCLA (University of California Los Angeles) activity score, performance of daily living activities, and opioid utilization.

RESULTS

No differences between groups were seen in opioid utilization, either during the acute hospitalization or in the eight weeks after surgery. The QS group reported significantly less pain at rest on postoperative day one and with activity on day three (p = 0.04 for each). Compared with baseline, both groups showed significant improvements in the KSS at one month (MPPA, p = 0.0278; QS, p = 0.0021) and three months (p < 0.0001 for each) as well as week-to-week gains in walking independence through five weeks after surgery. Independence from ambulatory devices outside the home lagged behind independence indoors by about two weeks in both groups.

CONCLUSIONS

When primary total knee arthroplasty was performed with contemporary minimally invasive surgery principles and standardized implants, anesthesia, and postoperative pathways, the QS technique yielded no significant early functional advantages or differences in opioid utilization compared with the MPPA technique. However, the mean pain scores reported by patients in the QS group were slightly lower at rest on postoperative day one and during activity on day three.

LEVEL OF EVIDENCE

Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

在初次全膝关节置换术后,减少对膝关节伸肌机制损伤的技术可能会减轻疼痛,并使膝关节功能恢复得更快。将全膝关节置换术的股四头肌保留(QS)股薄肌下入路技术与髌旁内侧关节切开术(MPPA)进行比较,以确定哪种手术技术能带来更好的患者报告功能、更少的术后疼痛和阿片类药物使用量。

方法

在这项前瞻性、双盲研究中,129例行全膝关节置换术的患者在皮肤切开后被随机分为QS组或MPPA组。所有手术均采用微创手术原则以及标准化的麻醉、植入物、镇痛和康复措施。在基线、术后1个月和3个月时获取膝关节协会评分(KSS)。每周通过电话访谈收集患者报告的结果,包括行走辅助装置的使用情况、加州大学洛杉矶分校(UCLA)活动评分、日常生活活动表现以及阿片类药物使用情况。

结果

在急性住院期间或术后8周内,两组在阿片类药物使用方面未见差异。QS组在术后第1天静息时和第3天活动时报告的疼痛明显更少(每项p = 0.04)。与基线相比,两组在1个月时(MPPA组,p = 0.0278;QS组,p = 0.0021)和3个月时(每组p < 0.0001)KSS均有显著改善,并且在术后5周内每周的行走独立性都有提高。两组在户外独立于行走辅助装置的时间比在室内落后约两周。

结论

当按照当代微创手术原则以及标准化植入物、麻醉和术后路径进行初次全膝关节置换术时,与MPPA技术相比,QS技术在早期功能方面没有显著优势,在阿片类药物使用方面也无差异。然而,QS组患者报告的平均疼痛评分在术后第1天静息时和第3天活动时略低。

证据水平

治疗性I级。有关证据水平的完整描述,请参阅作者指南。

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