Weber Benjamin, Seal Alexa, McGirr Joe, Fielding Kerin
Rural Clinical School, School of Medicine Sydney, The University of Notre Dame Australia, Wagga Wagga, New South Wales, Australia.
ANZ J Surg. 2016 Oct;86(10):796-800. doi: 10.1111/ans.12702. Epub 2014 Jun 5.
Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in orthopaedic surgery. While specific guidelines exist for hip and knee arthroplasty, there is wide variation in VTE prophylaxis in complex spinal surgery. This study sought to determine the incidence of VTE, and risk factors associated with VTE, in patients undergoing elective instrumented posterior lumbar spinal fusion.
In a single-centre case series study, 107 consecutive patients undergoing elective lumbar spinal fusion were evaluated for VTE by lower limb duplex ultrasonography and/or clinical observation, and where indicated, computed tomography pulmonary angiogram. The Caprini model for thrombosis risk factor assessment was retrospectively applied to grade levels of VTE risk, which were compared with overall VTE incidence.
All patients were operated on a spinal frame and received mechanical prophylaxis (thromboembolic deterrent stockings and sequential calf-compression devices). Thirty-seven per cent also received chemoprophylaxis with low-molecular-weight heparin (LMWH). There was no significant relationship between LMWH use and protection from VTE. Risk scores ≥3 (high/highest risk categories) were observed in 96.2% of patients. Four (3.7%) patients encountered a VTE complication (all with no chemoprophylaxis), either deep vein thrombosis (1.9%) or pulmonary embolism (1.9%). No patients sustained an epidural haematoma.
Although patients undergoing elective instrumental posterior lumbar spinal fusion are at high risk of developing VTE, the actual incidence of VTE in these patients is low. Our data support the use of mechanical prophylaxis with thromboembolic deterrent stockings and sequential calf-compression devices to prevent VTE in these patients.
静脉血栓栓塞症(VTE)是骨科手术中发病和死亡的重要原因。虽然针对髋关节和膝关节置换术有特定指南,但复杂脊柱手术中VTE预防措施差异很大。本研究旨在确定择期后路腰椎内固定融合术患者中VTE的发生率以及与VTE相关的危险因素。
在一项单中心病例系列研究中,通过下肢双功超声和/或临床观察对107例连续接受择期腰椎融合术的患者进行VTE评估,并在必要时进行计算机断层扫描肺血管造影。回顾性应用Caprini血栓形成危险因素评估模型对VTE风险等级进行分级,并与总体VTE发生率进行比较。
所有患者均在脊柱框架上进行手术,并接受机械预防(血栓栓塞防护袜和连续小腿压迫装置)。37%的患者还接受了低分子量肝素(LMWH)化学预防。使用LMWH与预防VTE之间无显著关系。96.2%的患者风险评分≥3(高/最高风险类别)。4例(3.7%)患者出现VTE并发症(均未接受化学预防),其中深静脉血栓形成(1.9%)或肺栓塞(1.9%)。无患者发生硬膜外血肿。
尽管接受择期后路腰椎内固定融合术的患者发生VTE的风险很高,但这些患者中VTE的实际发生率较低。我们的数据支持使用血栓栓塞防护袜和连续小腿压迫装置进行机械预防,以防止这些患者发生VTE。