Otake S, Kato H, Kurihara N, Yamamoto M, Kuroki T, Makimura M
Nichidai Koko Kagaku. 1989 Sep;15(3):342-6.
Serum antibody titers to lipopolysaccharide from Bacteroides intermedius (B. intermedius) and Bacteroides gingivalis (B. gingivalis) were measured by enzyme-linked immunosorbent assay in serum samples from subjects with healthy gingiva and patients with periodontitis. The IgG antibody titers to LPS from B. gingivalis were significantly higher in the patients group, compared with healthy controls. No such difference was found between IgG activity to LPS from B. intermedius in the healthy and the periodonitis. Likewise, no significant difference in specific IgA level was found between the group with healthy gingiva and the patients group, both in LPS from B. intermedius and B. gingivalis. The IgM antibody levels to LPS from B. intermedius and B. gingivalis were low in subjects of patients and controls.
通过酶联免疫吸附测定法，对健康牙龈受试者和牙周炎患者的血清样本中，针对中间普氏菌（B. intermedius）和牙龈卟啉单胞菌（B. gingivalis）脂多糖的血清抗体滴度进行了测量。与健康对照组相比，患者组中针对牙龈卟啉单胞菌脂多糖的IgG抗体滴度显著更高。在健康组和牙周炎组中，针对中间普氏菌脂多糖的IgG活性未发现此类差异。同样，在健康牙龈组和患者组之间，无论是针对中间普氏菌还是牙龈卟啉单胞菌的脂多糖，特异性IgA水平均未发现显著差异。患者和对照组受试者中，针对中间普氏菌和牙龈卟啉单胞菌脂多糖的IgM抗体水平均较低。
