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[摩洛哥一项关于血液透析患者丙型肝炎病毒感染的患病率及危险因素的研究结果]

[Prevalence and risk factors of hepatitis C virus infection in patients on hemodialysis: results of a Moroccan study].

作者信息

Doblali T, Bahadi A, El Amrani M, Benyahia M

机构信息

Laboratoire pôle biologie hôpital militaire d'instruction Mohamed-V, Rabat, Maroc.

Service de néphrologie, dialyse et transplantation rénale, hôpital militaire d'instruction Mohamed-V, Hay Ryad CP 1000, Rabat, Maroc.

出版信息

Med Sante Trop. 2014 Oct-Dec;24(4):375-8. doi: 10.1684/mst.2014.0333.

DOI:10.1684/mst.2014.0333
PMID:24898543
Abstract

INTRODUCTION

Infection with the hepatitis C virus (HCV) is the leading cause of chronic hepatitis in patients on hemodialysis. The objective of this study was to determine the prevalence of infection with this virus and its main risk factors among chronic hemodialysis patients treated at the Mohammed V military teaching hospital in Rabat, Morocco.

PATIENTS AND METHODS

Retrospective study of 141 patients with chronic end-stage kidney disease receiving hemodialysis between April 2010 and September 2012, including testing for anti-HCV antibodies and HCV RNA.

RESULTS

The prevalence of HCV assessed by PCR in chronic hemodialysis patients treated at our hospital was 12.1%. Risk factors associated with this prevalence included duration of hemodialysis and transfusions.

CONCLUSION

The prevalence of HCV among patients receiving hemodialysis in Morocco is gradually declining and the most important risk factors (transfusions and duration of hemodialysis) are becoming progressively less important.

摘要

引言

丙型肝炎病毒(HCV)感染是接受血液透析患者慢性肝炎的主要病因。本研究的目的是确定在摩洛哥拉巴特穆罕默德五世军事教学医院接受治疗的慢性血液透析患者中该病毒的感染率及其主要危险因素。

患者与方法

对2010年4月至2012年9月期间接受血液透析的141例慢性终末期肾病患者进行回顾性研究,包括检测抗-HCV抗体和HCV RNA。

结果

我院治疗的慢性血液透析患者中通过PCR评估的HCV感染率为12.1%。与该感染率相关的危险因素包括血液透析时间和输血。

结论

摩洛哥接受血液透析患者中的HCV感染率正在逐渐下降,最重要的危险因素(输血和血液透析时间)的重要性也在逐渐降低。

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