Selm Salem Bin
Faculty of Medicine and Health Sciences, Aden University, Aden, Yemen.
Saudi J Kidney Dis Transpl. 2010 Nov;21(6):1165-8.
To evaluate the prevalence of anti-hepatitis C virus (HCV) among the hemodialysis patients and to identify the risk factors of infection in relation to age, sex, blood transfusions, duration of dialysis and primary cause of end stage-kidney disease. We studied 51 patients who were on chronic hemodialysis (HD) at the Al-Gamhourea Teaching Hospital, Aden, Yemen, during Jan-Dec 2007. All the patients were tested for anti-HCV antibody, and we used 100 healthy blood donors as controls. The anti-HCV antibody prevalence rate among the HD patients was found to be significantly higher than that in the control group (62.7% and 0.8%, respectively). The prevalence rate of anti-HCV antibody was higher among men (64%) than that in women (35%). The anti-HCV antibody-positive patients were significantly older than the anti-HCV-antibody-negative patients (66.5 ± 14.4 years versus 57.5 ± 15.4 years; P = 0.01). Diabetic nephropathy was a more frequent cause of end-stage renal disease among the anti-HCV antibody-positive patients (30%) than among the anti-HCV antibody-negative patients (19%). Among the anti-HCV-positive patients, 80% had received a blood transfusion, which was significantly higher than the 20% rate among the anti-HCV antibody-negative patients (P < 0.001).
评估血液透析患者中抗丙型肝炎病毒（HCV）的流行情况，并确定与年龄、性别、输血、透析时间和终末期肾病主要病因相关的感染危险因素。我们研究了2007年1月至12月期间在也门亚丁的Al-Gamhourea教学医院接受慢性血液透析（HD）的51例患者。所有患者均检测了抗HCV抗体，我们使用100名健康献血者作为对照。发现HD患者中抗HCV抗体的患病率显著高于对照组（分别为62.7%和0.8%）。男性抗HCV抗体的患病率（64%）高于女性（35%）。抗HCV抗体阳性患者的年龄显著大于抗HCV抗体阴性患者（66.5±14.4岁对57.5±15.4岁；P=0.01）。在抗HCV抗体阳性患者中，糖尿病肾病作为终末期肾病的病因比抗HCV抗体阴性患者更为常见（30%对19%）。在抗HCV阳性患者中，80%接受过输血，这一比例显著高于抗HCV抗体阴性患者中的20%（P<0.001）。
