Stefanović G, Milosević-Jovcić N
Stomatol Glas Srb. 1989 Nov-Dec;36(5):409-18.
The significance of human dental plaque proteins that are of endogenous origin, probably serum or saliva, is still not clear. Little is known about the physico-chemical and immunochemical properties of plaque proteins. This information, however, might be of significance for a better understanding of the possible role of plaque proteins in the aethiology of some oral diseases. The purpose of this work was to identify several proteins in dental plaque of healthy people as well as to investigate the immunochemical similarity of these proteins with appropriate serum or saliva proteins. The results showed that with the exception of IgG all the other proteins detected in plaque were immunochemically identical with the appropriate serum or saliva proteins. The presence of IgG in plaque revealed immunochemical dissimilarity with partial identity with serum IgG. It was established that IgG plaque had no Fc portion. The results were discussed from the current point of view to the problem of immunochemical similarity between proteins in general, as well as from the aspect of specificity of used antisera.
源于人体自身、可能来自血清或唾液的牙菌斑蛋白质的重要性仍不明确。人们对牙菌斑蛋白质的物理化学和免疫化学性质了解甚少。然而，这些信息对于更好地理解牙菌斑蛋白质在某些口腔疾病病因学中可能发挥的作用或许具有重要意义。这项工作的目的是鉴定健康人牙菌斑中的几种蛋白质，并研究这些蛋白质与相应血清或唾液蛋白质的免疫化学相似性。结果表明，除IgG外，在牙菌斑中检测到的所有其他蛋白质与相应血清或唾液蛋白质在免疫化学上是相同的。牙菌斑中IgG的存在显示出与血清IgG部分相同的免疫化学差异。已确定牙菌斑IgG没有Fc部分。从目前关于蛋白质总体免疫化学相似性问题的角度，以及从所用抗血清特异性的方面对结果进行了讨论。
