Makis William, Rush Christopher
Department of Nuclear Medicine, Brandon Regional Health Centre, 150 McTavish Ave E, Brandon, MB R7A 2B3 Canada.
Department of Nuclear Medicine, Jewish General Hospital, McGill University, 3755 Cote Ste Catherine Road, Montreal, QC H3T 1E2 Canada.
Nucl Med Mol Imaging. 2011 Sep;45(3):220-2. doi: 10.1007/s13139-011-0088-6. Epub 2011 Jun 10.
Mycobacterium simiae (M. simiae) is an opportunistic pathogen rarely associated with human disease, although in recent years M. simiae has been detected with increasing frequency in human immunodeficiency virus (HIV)-infected patients, usually causing disseminated infection with fever, diarrhea and weight loss. We report the case of an HIV-positive man, who was referred for an (18)F-FDG PET/CT to evaluate a solitary pulmonary nodule. The PET/CT showed incidental large necrotic cervical lymph nodes, compatible with necrotizing cervical lymphadenitis. Biopsy and culture of one of the affected lymph nodes were positive for M. simiae. We present the first report of (18)F-FDG PET/CT imaging of an infectious process caused by M. simiae in humans.
猿分枝杆菌（M. simiae）是一种机会致病菌，很少与人类疾病相关，尽管近年来在感染人类免疫缺陷病毒（HIV）的患者中检测到猿分枝杆菌的频率越来越高，通常会引起伴有发热、腹泻和体重减轻的播散性感染。我们报告了一例HIV阳性男性病例，该患者因进行（18）F-FDG PET/CT检查以评估一个孤立性肺结节而前来就诊。PET/CT显示偶然发现的颈部大坏死淋巴结，符合坏死性颈淋巴结炎。对其中一个受影响的淋巴结进行活检和培养，结果显示猿分枝杆菌呈阳性。我们首次报告了猿分枝杆菌引起的人类感染性病变的（18）F-FDG PET/CT成像。
