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通过连续F-18 FDG PET/CT监测一例肺外结核的治疗反应

Monitoring Therapeutic Response in a Case of Extrapulmonary Tuberculosis by Serial F-18 FDG PET/CT.

作者信息

Park Yong Hyun, Yu Chang Min, Kim Eun Sil, Jung Jun Oh, Seo Han Seok, Lee Ju Hyoung, Hur So Chong, Kim So Yeon, Lee Hyon Young

机构信息

Department of Internal Medicine, National Police Hospital, Ga-rak Bon Dong, 58, Songpa Gu Seoul, 138-708 Korea.

Department of Nuclear Medicine, National Police Hospital, Seoul, Korea.

出版信息

Nucl Med Mol Imaging. 2012 Mar;46(1):69-72. doi: 10.1007/s13139-011-0114-8. Epub 2011 Nov 10.

Abstract

Due to the low yield of AFB smear and culture in extrapulmonary tuberculosis, therapeutic responses of patients with extrapulmonary tuberculosis are usually monitored clinically and/or radiographically. Such monitoring techniques, however, are not enough to provide effective diagnosis if a remnant lesion exists after treatment. Tuberculosis presents hypermetabolic activity on F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) scanning. Reported herein is a case of extrapulmonary tuberculosis where the therapeutic response was assessed via serial F-18 FDG PET/CT scanning, which was useful for detecting the extent of extrapulmonary tuberculosis and for estimating the patient's therapeutic response.

摘要

由于肺外结核中抗酸杆菌涂片和培养的阳性率较低,肺外结核患者的治疗反应通常通过临床和/或影像学进行监测。然而,如果治疗后存在残留病变,这些监测技术不足以提供有效的诊断。结核病在F-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(F-18 FDG PET/CT)扫描中表现为高代谢活性。本文报告一例肺外结核病例,通过连续的F-18 FDG PET/CT扫描评估治疗反应,这有助于检测肺外结核的范围并估计患者的治疗反应。

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本文引用的文献

1
Biomarkers for tuberculosis disease activity, cure, and relapse.
Lancet Infect Dis. 2010 Feb;10(2):69-70; author reply 70-1. doi: 10.1016/S1473-3099(09)70256-7.
10

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