Makis William, Alabed Yazan Z, Nahal Ayoub, Novales-Diaz Javier A, Hickeson Marc
Department of Nuclear Medicine, Brandon Regional Health Centre, 150 McTavish Ave E, Brandon, MB R7A 2B3 Canada.
Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Ave West, M2, Montreal, QC H3A 1A1 Canada.
Nucl Med Mol Imaging. 2012 Jun;46(2):134-7. doi: 10.1007/s13139-012-0134-z. Epub 2012 Apr 21.
A 59-year-old man with a 30-year history of multiple recurrences of a giant cell tumor (GCT) of the left knee was referred for an (18)F-FDG PET/CT to evaluate a solitary pulmonary nodule. The nodule was mildly FDG-avid, raising suspicion of malignancy. It was excised and histologically proven to be a GCT pulmonary metastasis. A follow-up PET/CT done 2 years later revealed a new, larger lung mass that was more intensely FDG-avid, but of the same histology. This rare report highlights a pitfall in the evaluation of solitary pulmonary lesions by (18)F-FDG PET/CT in patients with GCT of the bone.
一名59岁男性,左膝巨细胞瘤(GCT)有30年多次复发史,因评估一个孤立性肺结节而接受(18)F-FDG PET/CT检查。该结节有轻度FDG摄取,引起了对恶性肿瘤的怀疑。结节被切除,组织学证实为GCT肺转移。两年后进行的随访PET/CT显示一个新的、更大的肺肿块,FDG摄取更强烈,但组织学相同。这份罕见的报告强调了在骨GCT患者中通过(18)F-FDG PET/CT评估孤立性肺病变时的一个陷阱。