Kong Eun-Jung, Chun Kyung-Ah, Jeong Ju-Hye, Cho Ihn-Ho
Department of Nuclear Medicine, Yeungnam University Hospital, Namgu Daemyung 5-dong 317-1, 705-717 Daegu, South Korea.
Nucl Med Mol Imaging. 2013 Jun;47(2):119-24. doi: 10.1007/s13139-013-0200-1. Epub 2013 Apr 10.
Constraint-induced movement therapy (CIMT) was shown recently to be promising for improving upper-limb function in children with cerebral palsy (CP). This study investigated the changes in cerebral perfusion with single-photon emission computerized tomography (SPECT) after modified CIMT (child-friendly CIMT) in young hemiplegic girls. Two young children with left hemiplegic CP were studied with SPECT at rest before and after the CIMT period, and they also performed standardized upper motor function tests [Jebsen hand function test, quality of upper extremity skills test (QUEST), and dynamic electromyography (EMG)]. The cerebral perfusion SPECT revealed regional perfusion increase in the motor cortex area in the affected hemisphere, and the changes associated with functional gain. Our cases showed that intensive movement therapy appears to change local cerebral perfusion and SPECT could show these changes in children with hemiplegic CP.
最近研究表明，强制性运动疗法（CIMT）有望改善脑瘫（CP）患儿的上肢功能。本研究调查了改良CIMT（儿童友好型CIMT）对偏瘫女童脑灌注的影响，采用单光子发射计算机断层扫描（SPECT）进行检测。在CIMT治疗前后，对两名左侧偏瘫的CP幼儿进行了静息状态下的SPECT检查，同时他们还进行了标准化的上肢运动功能测试[杰布森手功能测试、上肢技能质量测试（QUEST）和动态肌电图（EMG）]。脑灌注SPECT显示，患侧半球运动皮层区域的灌注增加，且这些变化与功能改善相关。我们的病例表明，强化运动疗法似乎会改变局部脑灌注，SPECT能够显示偏瘫CP患儿的这些变化。
