Topaloglu Serdar, Ozturk M Halil
Hepatogastroenterology. 2014 Mar-Apr;61(130):398-404.
The liver is the most common site for neuroendocrine tumor metastasis. The characteristic feature of these tumors is related to the secretion of biologically active compounds in large amounts. Systemic chemotherapy has limited success in treating patients with neuroendocrine liver metastasis. Surgical management remains the only potentially curative option for these patients. According to the high incidence of recurrence after surgery, the role of intra-arterial therapy (IATs) in neuroendocrine tumor metastasis has been evolved. This review evaluates the potential role of IATs in the light of current literature.
肝脏是神经内分泌肿瘤转移最常见的部位。这些肿瘤的特征与大量生物活性化合物的分泌有关。全身化疗在治疗神经内分泌肝转移患者方面成效有限。手术治疗仍然是这些患者唯一可能治愈的选择。鉴于手术后复发率高,动脉内治疗(IATs)在神经内分泌肿瘤转移中的作用得到了发展。本综述根据当前文献评估IATs的潜在作用。