Roma Andres A, Barry Jessica, Pai Rish K, Billings Steven D
Department of Anatomic Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
Int J Gynecol Pathol. 2014 Jul;33(4):437-42. doi: 10.1097/PGP.0b013e31829ff21e.
Sebaceous gland hyperplasia is a common skin condition, very rarely reported in the female genital region. We present 13 cases from 12 patients, the first case series of sebaceous gland hyperplasia of the vulva. Differences in age at presentation and clinical presentation compared with classic sebaceous gland hyperplasia from the head and neck region were noted. Also, it was rarely included in the clinical differential diagnosis. Immunohistochemical studies to determine any possible association with the Muir-Torre syndrome were performed and mismatch repair protein loss was not identified.
皮脂腺增生是一种常见的皮肤疾病，在女性生殖器区域极为罕见。我们报告了来自12例患者的13个病例，这是外阴皮脂腺增生的首个病例系列。我们注意到，与头颈部的经典皮脂腺增生相比，其发病年龄和临床表现存在差异。此外，它很少被纳入临床鉴别诊断。我们进行了免疫组化研究以确定其与穆尔-托雷综合征的任何可能关联，但未发现错配修复蛋白缺失。
