Dermatopathology Group, Department of Anatomical Pathology, PathWest, Perth, Australia; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Dermatopathology Group, Department of Anatomical Pathology, PathWest, Perth, Australia; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Pathology. 2017 Dec;49(7):688-697. doi: 10.1016/j.pathol.2017.08.012. Epub 2017 Oct 25.
Sebaceous differentiation is commonly seen in cutaneous neoplasms, both in the context of lesions showing predominantly sebaceous differentiation (e.g., sebaceous adenoma, sebaceoma and sebaceous carcinoma), or as more focal sebaceous components in neoplasms with other primary lines of differentiation. Sebaceous changes can also be a component of benign cystic lesions or epidermal tumours, and sebaceous hyperplasia is commonly encountered. This review is intended to provide an overview of the cutaneous lesions with sebaceous differentiation, with a particular emphasis on facilitating histological diagnosis of neoplasms. In addition, the role of immunohistochemical studies is outlined, as well as the evaluation of potential cases of Muir-Torre syndrome.
皮脂分化在皮肤肿瘤中很常见，包括主要表现为皮脂分化的病变（例如，皮脂腺瘤、皮脂瘤和皮脂癌），以及在具有其他分化为主线的肿瘤中更集中的皮脂成分。皮脂变化也可以是良性囊性病变或表皮肿瘤的组成部分，并且常见皮脂增生。本综述旨在概述具有皮脂分化的皮肤病变，特别强调促进肿瘤的组织学诊断。此外，还概述了免疫组织化学研究的作用以及 Muir-Torre 综合征潜在病例的评估。
