Mortazavi Hossein, Soori Tahereh, Khamesipour Ali, Khatami Alireza, Vasheghani-Farahani Amir
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran AND Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Infectious Diseases, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Acta Med Iran. 2014;52(3):231-3.
Herein, a 12-year-old Afghan boy with chronic cutaneous leishmaniasis on the face and verrucous lesions on the body and pleural effusion suspected of having co-existent tuberculosis has been presented. The cutaneous lesions were appeared for five years before his admission. Leishman-Donovan bodies were seen in H&E (Hematoxylin and eosin) slide of skin lesion specimens. The pathogenic species was proved to be Leishmania tropica using Polymerase Chain Reaction (PCR) method. Purified Protein Derivative (PPD) and Leishmanin Skin Test (LST) were strongly positive. The patient was treated with systemic and intralesional meglumine antimoniate (Glucantime) for cutaneous leishmaniasis and then with anti-tuberculosis drugs for pleural effusion. Afterwards, pleural effusion was disappeared and cutaneous leishmaniasis cured.
本文介绍了一名12岁的阿富汗男孩，其面部患有慢性皮肤利什曼病，身体有疣状病变，且胸腔积液疑似合并肺结核。皮肤病变在他入院前已出现五年。在皮肤病变标本的苏木精和伊红（H&E）切片中可见利杜体。使用聚合酶链反应（PCR）方法证实致病物种为热带利什曼原虫。纯化蛋白衍生物（PPD）和利什曼菌素皮肤试验（LST）均呈强阳性。该患者接受了全身和皮损内注射葡甲胺锑酸盐（葡酸锑钠）治疗皮肤利什曼病，随后使用抗结核药物治疗胸腔积液。此后，胸腔积液消失，皮肤利什曼病治愈。
