Cıraklı Alper, Elli Murat, Dabak Nevzat, Canbaz Tosun Fevziye, Dağdemir Ayhan, Cıraklı Sevgi
Department of Orthopedics and Traumatology, Suluova State Hospital, Amasya, Turkey.
Department of Pediatrics, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey.
Acta Orthop Traumatol Turc. 2014;48(3):371-8. doi: 10.3944/AOTT.2014.3014.
Primary lymphoma of the bone is an extremely rare tumor in the form of non-Hodgkin lymphoma or Hodgkin lymphoma. The majority of primary bone lymphomas are non-Hodgkin lymphoma, of which the most common subtype is diffuse large cell lymphoma. Patients can present with pain, swelling or pathologic fracture. Definitive diagnosis is made after biopsy examination. Treatment consists of chemotherapy, radiotherapy and surgery. We report 3 male patients who presented with pain and swelling. Involvement was in the distal femur, proximal fibula and iliac crest in all patients. Patients were diagnosed with non-Hodgkin lymphoma in biopsy examination and underwent chemotherapy. The patient with distal femoral involvement underwent distal femoral resection prosthesis. Another patient with involvement of the fibular head experienced foot drop and delayed wound healing. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography revealed complete response to the treatment. Patients are in remission and continue schooling.
原发性骨淋巴瘤是一种极为罕见的肿瘤，呈非霍奇金淋巴瘤或霍奇金淋巴瘤的形式。大多数原发性骨淋巴瘤是非霍奇金淋巴瘤，其中最常见的亚型是弥漫性大细胞淋巴瘤。患者可出现疼痛、肿胀或病理性骨折。经活检检查后作出明确诊断。治疗包括化疗、放疗和手术。我们报告3例男性患者，他们均表现为疼痛和肿胀。所有患者的病变部位均在股骨远端、腓骨近端和髂嵴。患者经活检检查诊断为非霍奇金淋巴瘤并接受了化疗。股骨远端受累的患者接受了股骨远端切除假体手术。另一例腓骨头受累的患者出现足下垂和伤口愈合延迟。氟-18-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描显示治疗取得完全缓解。患者处于缓解期并继续上学。
