Xiao Hua-Feng, Lou Xin, Liu Meng-Yu, Wang Yu-Lin, Wang Yan, Chen Zhi-Ye, Shi Kai-Ning, Ma Lin
Department of Radiology, PLA General Hospital, Beijing, China.
General Electric Company GE (China) Co., Ltd, Healthcare, Beijing, China.
J Int Med Res. 2014 Aug;42(4):915-25. doi: 10.1177/0300060514531918. Epub 2014 Jun 5.
To evaluate the diagnostic value of magnetic resonance diffusion-weighted imaging (DWI) and three-dimensional arterial spin labelling perfusion imaging (3D-ASL) in distinguishing cavernous haemangioma from parasellar meningioma, using histological data as a reference standard.
Patients with parasellar meningioma or parasellar cavernous haemangioma underwent conventional T1- and T2-weighted magnetic resonance imaging (MRI) followed by DWI and 3D-ASL using a 3.0 Tesla MRI. The minimum apparent diffusion coefficient (minADC) from DWI and the maximal normalized cerebral blood flow (nCBF) from 3D-ASL were measured in each tumour. Diagnosis was confirmed by histology.
MinADC was significantly lower and nCBF significantly higher in meningioma (n = 19) than cavernous haemangioma (n = 15). There was a significant negative correlation between minADC and nCBF (r = -0.605).
DWI and 3D-ASL are useful in differentiating cavernous haemangiomas from parasellar meningiomas, particularly in situations when the appearance on conventional MRI sequences is otherwise ambiguous.
以组织学数据作为参考标准，评估磁共振扩散加权成像（DWI）和三维动脉自旋标记灌注成像（3D-ASL）在鉴别海绵状血管瘤与鞍旁脑膜瘤中的诊断价值。
鞍旁脑膜瘤或鞍旁海绵状血管瘤患者先接受常规T1加权和T2加权磁共振成像（MRI）检查，然后使用3.0特斯拉MRI进行DWI和3D-ASL检查。在每个肿瘤中测量DWI的最小表观扩散系数（minADC）和3D-ASL的最大标准化脑血流量（nCBF）。通过组织学确诊。
脑膜瘤（n = 19）的minADC显著低于海绵状血管瘤（n = 15），nCBF显著高于海绵状血管瘤。minADC与nCBF之间存在显著负相关（r = -0.605）。
DWI和3D-ASL有助于鉴别海绵状血管瘤与鞍旁脑膜瘤，特别是在常规MRI序列表现不明确的情况下。
