Nogueira Solange A, Dimenstein Renato, Cunha Marcelo L, Wagner Jairo, Funari Marcelo B G, Lederman Henrique M
Departamento de Imagem, Hospital Israelita Albert Einstein, Av. Albert Einstein, 627-Morumbi, São Paulo, SP, 05652-000, Brazil,
Radiol Med. 2015 Feb;120(2):251-5. doi: 10.1007/s11547-014-0422-z. Epub 2014 Jun 6.
The use of positron emission tomography combined with computed tomography (PET/CT) has brought about significant technological advancement in diagnostic imaging, and a number of PET/CT scanners with bismuth germanate detectors can perform imaging in both 2D and 3D acquisition modes. Nevertheless, certain image acquisition parameters and physical features of patients have to be considered when designing low-dose protocols in the 3D mode.
The aim of this study was to compare images acquired in 2D and 3D modes and establish a low-dose protocol for use in PET/CT imaging, decreasing patient exposure to radiation without compromising results.
A total of 30 patients, aged 4-72 years, participated in this prospective study, which was conducted at Albert Einstein Hospital, São Paulo, Brazil. Images were evaluated for picture quality, presence/absence of lesions and the number of lesions that were detectable in both acquisition modes.
The results consistently showed that the loss in image quality in the 3D mode did not affect exam interpretation and lesion detection when compared with 2D at higher dose and for a longer time.
We therefore conclude that administration of 3.7 MBq [(18)F]-fluorodeoxyglucose (FDG)/kg for an acquisition time of 3 min per FOV (field of view) is optimal for image acquisition in the 3D mode. This protocol, which reduces the acquisition time and radiation dose, is quite beneficial, especially for children.
正电子发射断层扫描与计算机断层扫描相结合（PET/CT）的应用在诊断成像领域带来了重大技术进步，许多配备锗酸铋探测器的PET/CT扫描仪能够在二维和三维采集模式下进行成像。然而，在设计三维模式下的低剂量方案时，必须考虑某些图像采集参数和患者的身体特征。
本研究旨在比较二维和三维模式下采集的图像，并建立一种用于PET/CT成像的低剂量方案，在不影响结果的情况下减少患者的辐射暴露。
共有30名年龄在4至72岁之间的患者参与了这项前瞻性研究，该研究在巴西圣保罗的阿尔伯特·爱因斯坦医院进行。对两种采集模式下图像的画质、病变的有无以及可检测到的病变数量进行评估。
结果一致表明，与二维模式在更高剂量和更长时间下相比，三维模式下的图像质量损失并未影响检查解读和病变检测。
因此，我们得出结论，对于三维模式下的图像采集，每视野（FOV）给予3.7 MBq [（18）F] - 氟脱氧葡萄糖（FDG）/kg并采集3分钟是最佳方案。该方案减少了采集时间和辐射剂量，非常有益，尤其是对儿童而言。
