Tiberio G, Martí J, Iriarte M, Pérez C, Antón E, Maravi Petri E, Martínez Ibáñez F
Enferm Infecc Microbiol Clin. 1989 Aug-Sep;7(7):368-9.
We report 47 patients with purulent meningitis who were seen at our institution during the last 3 years. In 42.5% of patients an upper respiratory infection previous to the onset of the clinical features of meningitis was demonstrated. We had positive bacteriological results in 47% of cases. In the remaining patients the culture was negative. 56% of these had received previous antibiotic therapy. Only 4 patients died, all of them with initial septic shock. The therapy of choice was i.v. ampicillin, at a dose of 1-3 g/4 hours.
我们报告了过去3年在我院就诊的47例化脓性脑膜炎患者。42.5%的患者在脑膜炎临床症状出现前有上呼吸道感染。47%的病例细菌学检查结果为阳性。其余患者培养结果为阴性。其中56%曾接受过抗生素治疗。仅4例死亡,均为初始感染性休克患者。首选治疗药物为静脉注射氨苄西林,剂量为1 - 3g/4小时。