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多汗症:原发性多汗症的最新进展及新治疗选择综述

Hyperhidrosis: review of recent advances and new therapeutic options for primary hyperhidrosis.

作者信息

Brown Ashley L, Gordon Jennifer, Hill Samantha

机构信息

Department of Dermatology, University of Texas Southwestern-Austin, Austin, Texas, USA.

出版信息

Curr Opin Pediatr. 2014 Aug;26(4):460-5. doi: 10.1097/MOP.0000000000000108.

Abstract

PURPOSE OF REVIEW

Primary focal hyperhidrosis is a common condition that negatively impacts quality of life for many pediatric patients and can be challenging to treat. Standard treatments for hyperhidrosis can be used with success in many patients, and newer therapies and techniques offer options that have demonstrated efficacy and safety. This review highlights standard therapies for primary focal hyperhidrosis as well as the most recent technique advancements and alternative treatment options.

RECENT FINDINGS

The standard approach to treating primary focal hyperhidrosis remains initiation of topical preparations, followed by advancement to systemic medications, local administration of medication and/or surgical procedures. Recent studies focus on enhancing tolerability of topical preparations as well as evaluating the efficacy of neuromodulator injections, oral anticholinergic medications and laser therapy. Microwave technology has also been introduced for the treatment of focal hyperhidrosis with promising results.

SUMMARY

Many therapies exist for hyperhidrosis, and each treatment plan must be evaluated on a patient-by-patient basis. Advances in standard therapies and emergence of new treatment techniques are the main emphases of current published literature on hyperhidrosis. This article presents recent therapeutic options as well as updates on more established strategies to help practitioners treat this challenging condition.

摘要

综述目的

原发性局灶性多汗症是一种常见病症,对许多儿科患者的生活质量产生负面影响,且治疗颇具挑战性。多汗症的标准治疗方法在许多患者中可成功应用,新的疗法和技术也提供了已证明有效且安全的选择。本综述重点介绍原发性局灶性多汗症的标准疗法以及最新的技术进展和替代治疗方案。

最新发现

治疗原发性局灶性多汗症的标准方法仍是先使用外用制剂,随后进展到全身性药物、局部给药和/或外科手术。近期研究集中在提高外用制剂的耐受性以及评估神经调节剂注射、口服抗胆碱能药物和激光治疗的疗效。微波技术也已被引入用于治疗局灶性多汗症,效果 promising。

总结

多汗症有多种治疗方法,每个治疗方案都必须根据患者个体情况进行评估。标准疗法的进展和新治疗技术的出现是当前多汗症已发表文献的主要重点。本文介绍了近期的治疗选择以及更成熟策略的更新,以帮助从业者治疗这种具有挑战性的病症。

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