Munir Atif
Department of Diabetes and Endocrinology, University Hospital of North Tees, UK.
J Coll Physicians Surg Pak. 2014 May;24 Suppl 2:S99-100.
Periodic paralysis is a muscle disorder that belongs to the family of diseases called channelopathies, manifested by episodes of painless muscle weakness. Periodic paralysis is classified as hypokalemic when episodes occur in association with low potassium levels. Most cases are hereditary. Acquired cases have been described in association with hyperthyroidism. Diagnosis is made on clinical and biochemical grounds. Patients may be markedly hypokalemic during the episode and respond well to potassium supplementation. Episodes can be prevented by achieving a euthyroid state. This report describes a young gentleman presenting with thyrotoxic hypokalemic paraparesis. The condition needs to be considered in the differential diagnosis of neuromuscular weakness in the context of hypokalemia by the treating physicians.
周期性麻痹是一种属于离子通道病家族的肌肉疾病，表现为无痛性肌无力发作。当发作与低钾水平相关时，周期性麻痹被归类为低钾性。大多数病例是遗传性的。已描述了与甲状腺功能亢进相关的获得性病例。诊断基于临床和生化依据。患者在发作期间可能明显低钾，补充钾后反应良好。通过实现甲状腺功能正常状态可预防发作。本报告描述了一名患有甲状腺毒症性低钾性双侧轻瘫的年轻男性。治疗医生在鉴别诊断低钾血症背景下的神经肌肉无力时需要考虑这种情况。
