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用藻酸钠和淀粉混合物制备的粘质沙雷氏菌 Rs-2 微胶囊的特性及其释放行为。

Characterization of Raoultella planticola Rs-2 microcapsule prepared with a blend of alginate and starch and its release behavior.

机构信息

School of Chemistry and Chemical Engineering, Key Laboratory for Chemical Materials of Xinjiang Uygur Autonomous Region, Shihezi University, Shihezi 832003, PR China.

School of Chemistry and Chemical Engineering, Key Laboratory for Chemical Materials of Xinjiang Uygur Autonomous Region, Shihezi University, Shihezi 832003, PR China.

出版信息

Carbohydr Polym. 2014 Sep 22;110:259-67. doi: 10.1016/j.carbpol.2014.04.011. Epub 2014 Apr 18.

Abstract

To judiciously use Raoultella planticola Rs-2 and develop its biodegradable and controlled-release formulations, Rs-2 was encapsulated with various combinations of sodium alginate (NaAlg) and starch. Sodium alginate, soluble starch, and CaCl2 showed good biocompatibility with Rs-2 for preparing microcapsules. These microcapsules were spherical in shape and their particle size, embedding rate, swelling ratio of Rs-2 microcapsules and release numbers of viable Rs-2 cells increased with the increasing of starch and NaAlg concentrations. Meanwhile, the biodegradability of the microcapsules constantly increases when the wt% of starch increased, but decreased when the amount of NaAlg increased. In addition, the release mechanism of microcapsules was consistent with that of the Ritger-Peppas model, which involves the Case II diffusion mechanism. In summary, the desired properties of the microcapsules can be modulated by varying the starch and alginate amounts of capsule materials. This process has broad application prospects to meet the needs of agricultural production.

摘要

为了明智地利用鲁氏不动杆菌 Rs-2 并开发其可生物降解和控制释放制剂,将 Rs-2 用不同组合的海藻酸钠 (NaAlg) 和淀粉进行包封。海藻酸钠、可溶性淀粉和 CaCl2 对 Rs-2 制备微胶囊表现出良好的生物相容性。这些微胶囊呈球形,其粒径、包埋率、Rs-2 微胶囊的溶胀比和活 Rs-2 细胞的释放数随淀粉和 NaAlg 浓度的增加而增加。同时,当淀粉的重量百分比增加时,微胶囊的生物降解性不断增加,但当 NaAlg 的量增加时,生物降解性降低。此外,微胶囊的释放机制与 Ritger-Peppas 模型一致,涉及到二级扩散机制。总之,通过改变胶囊材料中淀粉和藻酸盐的量可以调节微胶囊的所需性质。这个过程具有广阔的应用前景,可以满足农业生产的需求。

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