Otsuka Yoritaka, Murata Takashi, Kono Michiaki, Imoto Hiroki, Koyama Taku, Nakamura Keita, Kadama Sunao, Noguchi Hiroo, Saito Taro
Department of Cardiology, Fukuoka Wajiro Hospital, 2-2-75, Wajirogaoka, Higashi-ku, Fukuoka, 811-0213, Japan.
Heart Vessels. 2015 Sep;30(5):682-6. doi: 10.1007/s00380-014-0528-1. Epub 2014 Jun 7.
In-stent restenosis (ISR) has long remained as the major limitation of coronary stenting. The use of drug-eluting stent (DES) reduces the risk of repeat revascularization without an increase of death and myocardial infarction, compared to the standard bare metal stents. DES has also demonstrated markedly to reduce ISR for complex lesions. However, ISR after DES implantation still occurs and optimal treatment for ISR after DES has not been established. Herein, we report 3 cases with black hole restenosis confirmed by intravascular ultrasound at the site of overlapped DES and discuss potential mechanism and optimal strategy for this phenomenon.
支架内再狭窄（ISR）长期以来一直是冠状动脉支架置入术的主要限制因素。与标准裸金属支架相比，药物洗脱支架（DES）的使用降低了再次血管重建的风险，且未增加死亡和心肌梗死的风险。DES还显著降低了复杂病变的ISR。然而，DES植入后的ISR仍会发生，且尚未确立DES术后ISR的最佳治疗方法。在此，我们报告3例经血管内超声证实为DES重叠部位出现黑洞样再狭窄的病例，并讨论这种现象的潜在机制和最佳策略。
