特立尼达岛年龄、性别、种族、家族病史、肥胖及高血压与2型糖尿病的关联

The association of age, gender, ethnicity, family history, obesity and hypertension with type 2 diabetes mellitus in Trinidad.

作者信息

Nayak B Shivananda, Sobrian Arianne, Latiff Khalif, Pope Danielle, Rampersad Akash, Lourenço Kodi, Samuel Nichole

机构信息

The University of the West Indies, Faculty of Medical Sciences, Departments of Preclinical and Paraclinical Sciences, Trinidad and Tobago.

出版信息

Diabetes Metab Syndr. 2014 Apr-Jun;8(2):91-5. doi: 10.1016/j.dsx.2014.04.018. Epub 2014 May 23.

DOI:10.1016/j.dsx.2014.04.018

PMID:24907173

Abstract

AIMS

To assess the impact of risk factors such as age, gender, ethnicity, family history, body mass index (BMI), waist circumference and hypertension, on the development of type 2 diabetes mellitus in the Trinidadian population.

MATERIALS AND METHODS

A cross-sectional case control study comprised 146 non-diabetics and 147 type 2 diabetics ≥18 years of age, from North Central, South West and Eastern regions of Trinidad.

RESULTS

Cross-tabulations revealed a significant difference between type 2-diabetes and age at p<0.01, and between type 2 diabetes and family history, ethnicity, waist circumference and hypertension at p<0.05. Logistic regression showed age to be the most influential risk factor. The systolic blood pressure specifically showed a significant difference at p<0.05, with the mean values for non-diabetics and type 2 diabetics being, 130.62 (±2.124) and 141.35 (±2.312), respectively. No significant difference was observed between type 2 diabetes and gender and BMI.

CONCLUSIONS

Age was the most significant risk factor of type 2 diabetes. Therefore it can be concluded that family history, ethnicity, waist circumference and hypertension are more significant risk factors of this disease than BMI and gender in the Trinidadian population.

摘要

目的

评估年龄、性别、种族、家族病史、体重指数（BMI）、腰围和高血压等风险因素对特立尼达人群2型糖尿病发病的影响。

材料与方法

一项横断面病例对照研究，纳入了来自特立尼达中北部、西南部和东部地区的146名非糖尿病患者和147名年龄≥18岁的2型糖尿病患者。

结果

交叉表显示，2型糖尿病与年龄之间在p<0.01时有显著差异，2型糖尿病与家族病史、种族、腰围和高血压之间在p<0.05时有显著差异。逻辑回归显示年龄是最有影响力的风险因素。收缩压在p<0.05时显示出显著差异，非糖尿病患者和2型糖尿病患者的平均值分别为130.62（±2.124）和141.35（±2.312）。2型糖尿病与性别和BMI之间未观察到显著差异。