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特立尼达 2 型糖尿病患者的生化参数、BMI 和血压与年龄、性别和种族的关系。

Relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects.

机构信息

The University of the West Indies, Departments of Preclinical and Paraclinical Sciences, Trinidad and Tobago.

出版信息

Arch Physiol Biochem. 2012 Feb;118(1):10-5. doi: 10.3109/13813455.2011.613482. Epub 2011 Sep 30.

DOI:10.3109/13813455.2011.613482
PMID:21961500
Abstract

OBJECTIVE

To determine the relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects.

METHODS

A retrospective case control study comprised of 1794 patient (740 males and 1054 females).

RESULTS

The correlation was found for lipid profile with age and gender in diabetic subjects. There was a positive significant correlation in LDL-C values for all age groups. Serum creatinine concentrations significantly varied amongst ethnicity (p = 0.02). Of the known ethnicities, East Indians had the highest mean creatinine value (1.00 ± 0.47 mg/dl). The univariate general linear model showed that lipid profile had many associations with gender and ethnicity in type 2 diabetic subjects. LDL-C had significant differences between gender (p = 0.04) and diabetes (p = 0.01).

CONCLUSIONS

Varied lipid profile with elevated systolic blood pressure and BMI are associated in type 2 diabetic patients with respect to age, gender and ethnicity.

摘要

目的

确定特立尼达 2 型糖尿病患者的生化参数、BMI 和血压与年龄、性别和种族的关系。

方法

一项回顾性病例对照研究包括 1794 名患者(740 名男性和 1054 名女性)。

结果

在糖尿病患者中,血脂谱与年龄和性别存在相关性。所有年龄组的 LDL-C 值均呈正显著相关。血清肌酐浓度在种族之间存在显著差异(p=0.02)。在已知的种族中,东印度人肌酐值最高(1.00±0.47mg/dl)。单变量一般线性模型显示,血脂谱在 2 型糖尿病患者中与性别和种族有许多关联。LDL-C 在性别(p=0.04)和糖尿病(p=0.01)之间存在显著差异。

结论

2 型糖尿病患者的血脂谱不同,伴有血压升高和 BMI 升高,与年龄、性别和种族有关。

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