Vernaz S, Casanova L, Blanc F, Lebel S, Ughetto F, Paut O
Service de réanimation pédiatrique, hôpital de la Timone, faculté de médecine, université Aix-Marseille, 27, boulevard Jean-Moulin, 13005 Marseille, France.
Département de médecine générale, Aix-Marseille université, 27, boulevard Jean-Moulin, 13005, Marseille, France.
Ann Fr Anesth Reanim. 2014 Jun;33(6):400-4. doi: 10.1016/j.annfar.2014.04.007. Epub 2014 Jun 3.
Since 2005, forgoing live-support (FLS) is allowed by the French law (known as the Leonetti law) for end-of-life patients only. This study aims at describing the variations over time in the use of the following methods to end life: FLS, brain death and cardiopulmonary resuscitation failure (CPR failure). It is a single retrospective study from 2007 to 2012. The Cochran-Armitage trend test is used in the statistical analysis. Over six years, 263 of the 5100 children who were hospitalized in our intensive care unit died, which represents a 5.2% mortality rate. FLS increased yearly from 31% of the deaths in 2007, to 71% in 2012 (P=0.0008). The rate of CPR failure decreased over the same period (P=0.0015). The rate of brain death remained constant. Following to the Leonetti law, FLS increase, and palliative cares develop without any increase of mortality.
自2005年起，法国法律（即《莱奥内蒂法》）仅允许对临终患者放弃生命维持治疗（FLS）。本研究旨在描述以下结束生命方式的使用随时间的变化情况：放弃生命维持治疗、脑死亡和心肺复苏失败（CPR失败）。这是一项针对2007年至2012年的单中心回顾性研究。统计分析采用 Cochr an-Armitage趋势检验。六年间，在我们重症监护病房住院的5100名儿童中有263名死亡，死亡率为5.2%。放弃生命维持治疗的比例从2007年占死亡人数的31%逐年上升至2012年的71%（P=0.0008）。同期心肺复苏失败的比例下降（P=0.0015）。脑死亡的比例保持不变。根据《莱奥内蒂法》，放弃生命维持治疗的情况增加，姑息治疗得到发展，而死亡率并未上升。
