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Genes, the environment and personalized medicine: We need to harness both environmental and genetic data to maximize personal and population health.

作者信息

Carlsten Chris, Brauer Michael, Brinkman Fiona, Brook Jeffrey, Daley Denise, McNagny Kelly, Pui Mandy, Royce Diana, Takaro Tim, Denburg Judah

机构信息

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

School of Population and Public Health University of British Columbia, Vancouver, BC, Canada.

出版信息

EMBO Rep. 2014 Jul;15(7):736-9. doi: 10.15252/embr.201438480. Epub 2014 Jun 6.

DOI:10.15252/embr.201438480
PMID:24907240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4196974/
Abstract
摘要

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本文引用的文献

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GSTP1 and TNF Gene variants and associations between air pollution and incident childhood asthma: the traffic, asthma and genetics (TAG) study.谷胱甘肽S-转移酶P1（GSTP1）和肿瘤坏死因子（TNF）基因变异以及空气污染与儿童哮喘发病之间的关联：交通、哮喘与遗传学（TAG）研究
Environ Health Perspect. 2014 Apr;122(4):418-24. doi: 10.1289/ehp.1307459. Epub 2014 Jan 24.
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Abacavir pharmacogenetics--from initial reports to standard of care.阿巴卡韦药物遗传学——从最初的报告到标准治疗。
Pharmacotherapy. 2013 Jul;33(7):765-75. doi: 10.1002/phar.1278. Epub 2013 May 3.
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Medicine. (De)personalized medicine.医学。（去）个性化医疗。
Science. 2013 Mar 8;339(6124):1155-6. doi: 10.1126/science.1234106.
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The cost-effectiveness of environmental approaches to disease prevention.疾病预防环境方法的成本效益。
N Engl J Med. 2012 Jul 26;367(4):295-7. doi: 10.1056/NEJMp1206268.
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A population approach to precision medicine.精准医学的群体方法。
Am J Prev Med. 2012 Jun;42(6):639-45. doi: 10.1016/j.amepre.2012.02.012.
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P5 medicine: a plus for a personalized approach to oncology.精准医学：肿瘤个性化治疗的助力
Nat Rev Clin Oncol. 2011 May 31;8(7):444. doi: 10.1038/nrclinonc.2010.227-c1.
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Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment.常见复杂疾病的表观遗传学流行病学：预测、预防和治疗的前景。
PLoS Med. 2010 Oct 26;7(10):e1000356. doi: 10.1371/journal.pmed.1000356.
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Personalized medicine in the era of genomics.基因组学时代的个性化医疗。
JAMA. 2007 Oct 10;298(14):1682-4. doi: 10.1001/jama.298.14.1682.
9
Potential for genetics to promote public health: genetics research on smoking suggests caution about expectations.遗传学促进公众健康的潜力：关于吸烟的遗传学研究对预期提出了警示。
JAMA. 2006 Nov 22;296(20):2480-2. doi: 10.1001/jama.296.20.2480.
10
Effects of dog ownership and genotype on immune development and atopy in infancy.养狗及基因类型对婴儿期免疫发育和特应性的影响。
J Allergy Clin Immunol. 2004 Feb;113(2):307-14. doi: 10.1016/j.jaci.2003.11.017.