Love Shawn, Solomon Gary S
Vanderbilt University School of Medicine, Nashville, Tennessee, USA Vanderbilt Sports Concussion Center, Nashville, Tennessee, USA.
Vanderbilt University School of Medicine, Nashville, Tennessee, USA Vanderbilt Sports Concussion Center, Nashville, Tennessee, USA
Am J Sports Med. 2015 May;43(5):1260-4. doi: 10.1177/0363546514535187. Epub 2014 Jun 6.
Over the past decade, athletic-related chronic traumatic encephalopathy (CTE) has garnered a great deal of attention in the popular press and, more recently, in the scientific press. With increasing frequency, sports medicine practitioners and providers are faced with questions from the parents of high school football players about CTE and the risk posed to children who participate in this or other contact or collision sports. The purpose of this review was to summarize the research on CTE in an attempt to provide some evidence-based answers to frequently asked questions in clinics from parents. Addressed are (1) the definitions of CTE and its symptoms, (2) the evidence for CTE in football, (3) abnormal tau protein, (4) the use of neuroimaging in CTE diagnosis, (5) risk for CTE, (6) CTE diagnosis in youth, (7) CTE and its relationship to suicide, and (8) contact and collision sports as a risk factor for permanent brain injury or death.
在过去十年中，与运动相关的慢性创伤性脑病（CTE）在大众媒体，以及最近在科学媒体上都引起了广泛关注。运动医学从业者越来越频繁地面临高中橄榄球运动员家长关于CTE以及参与此项运动或其他接触性或碰撞性运动的儿童所面临风险的问题。本综述的目的是总结关于CTE的研究，试图为临床中家长们经常问到的问题提供一些基于证据的答案。内容包括：（1）CTE的定义及其症状，（2）橄榄球运动中CTE的证据，（3）异常tau蛋白，（4）神经影像学在CTE诊断中的应用，（5）CTE的风险，（6）青少年CTE的诊断，（7）CTE及其与自杀的关系，以及（8）接触性和碰撞性运动作为永久性脑损伤或死亡的风险因素。
