Thompson Amanda L, Houck Kelly M, Adair Linda, Gordon-Larsen Penny, Popkin Barry
Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Carolina Population Center, University of North Carolina at Chapel Hill, 123 W Franklin St, Chapel Hill, NC 27516, USA.
Carolina Population Center, University of North Carolina at Chapel Hill, 123 W Franklin St, Chapel Hill, NC 27516, USA; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Health Place. 2014 Jul;28:177-86. doi: 10.1016/j.healthplace.2014.05.003. Epub 2014 Jun 5.
We examine the associations between overall urbanicity and specific physical and social components of community-level urbanization with C-reactive protein (CRP) in adults participating in the China Health and Nutrition Study. Higher overall urbanicity and environment-related urbanicity component scores, including education, housing quality, and access to markets, were associated with elevated CRP in multilevel models controlling for clustering by community. These associations differed by age and gender and persisted after controlling for individual-level anthropometric, diet, and pathogenic risk factors. These results highlight the importance of place in relation to inflammation across the spectrum of rural and urban environments.
我们在中国健康与营养研究的成年参与者中，研究了总体城市化程度以及社区层面城市化的特定物质和社会组成部分与C反应蛋白（CRP）之间的关联。在控制了社区聚类的多层次模型中，较高的总体城市化程度以及与环境相关的城市化组成部分得分，包括教育、住房质量和市场可达性，均与CRP升高相关。这些关联因年龄和性别而异，在控制了个体层面的人体测量、饮食和致病风险因素后依然存在。这些结果凸显了在农村和城市环境范围内，地点对于炎症的重要性。
