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大动脉炎中罕见的关联及灾难性表现:一例尸检病例报告

Uncommon associations and catastrophic manifestation in Takayasu arteritis: an autopsy case report.

作者信息

Chougule Abhijit, Bal Amanjit, Das Ashim, Jain Sanjay, Bahl Ajay

机构信息

Department of Histopathology, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India.

Department of Histopathology, Post Graduate Institute of Medical Education & Research, (PGIMER), Sector - 12, Chandigarh- 160012, India.

出版信息

Cardiovasc Pathol. 2014 Sep-Oct;23(5):313-6. doi: 10.1016/j.carpath.2014.04.005. Epub 2014 May 2.

Abstract

Takayasu arteritis, a chronic inflammatory vasculitis affecting aorta and its major branches, is complicated by stenosis, occlusion, and aneurysm formation. The aneurysm formation and subsequent complications such as heart failure, aortic regurgitation, and aneurysm rupture can be fatal. The aortic aneurysm rupture is a rare and fatal complication with only a few cases reported in the English literature. The involvement of coronary artery in Takayasu occurs in about 10% patients, and the coronary artery aneurysm is the least common manifestation. Here, we describe a case of Takayasu arteritis with abdominal aortic aneurysm rupture and coronary artery aneurysm. This patient also had associated systemic inflammatory diseases like sarcoidosis and Hashimoto's thyroiditis.

摘要

高安动脉炎是一种影响主动脉及其主要分支的慢性炎症性血管炎,常并发狭窄、闭塞和动脉瘤形成。动脉瘤形成及随后出现的诸如心力衰竭、主动脉瓣关闭不全和动脉瘤破裂等并发症可能是致命的。主动脉瘤破裂是一种罕见且致命的并发症,英文文献中仅有少数病例报道。高安动脉炎患者中冠状动脉受累的情况约占10%,冠状动脉瘤是最不常见的表现形式。在此,我们描述一例高安动脉炎合并腹主动脉瘤破裂及冠状动脉瘤的病例。该患者还伴有结节病和桥本甲状腺炎等全身性炎症性疾病。

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