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氟滴剂给药对龋齿增量的影响——一项纵向研究。

The effect of fluoride drop administration on dental caries increment--a longitudinal study.

作者信息

Mann J, Horesh E, Ran F, Gedalia I

机构信息

Hebrew University, Jersualem, Israel.

出版信息

Isr J Dent Sci. 1989 Oct;2(3):148-52.

PMID:2490929
Abstract

The effect of fluoride drop supplementation was investigated in a longitudinal study initiated in 1980. The def-t and DMF-T indices were used to estimate the incremental caries rate of the deciduous and first molars of 211 children aged 7-8 and 9.5-10.5 years. No statistically significant differences between the experimental and control def-t and DMF-T scores were found after 3 years. The incremental caries rate of the deciduous dentition of the experimental group was found to be significantly lower than that of the control group (def-t = 0.61 and 1.07 respectively), whereas the difference in the caries increments of the first molars was not significant (DMF-T = 1.62 in both groups). It is estimated that the efficacy was due to the long-term cariostatic effect of the topically acting fluoride on the erupting primary dentition, whereas the permanent dentition (first molars) had already completed calcification of the crown, but had not erupted at initiation of the study. It was estimated that the most effective cariostatic benefits would be apparent in the late erupting teeth of this study group.

摘要

在一项始于1980年的纵向研究中,对补充氟滴剂的效果进行了调查。使用乳牙龋失补牙面数(def-t)和恒牙龋失补牙面数(DMF-T)指数来评估211名7 - 8岁以及9.5 - 10.5岁儿童乳牙和第一恒磨牙的龋齿发病率增长情况。3年后,实验组与对照组的def-t和DMF-T评分之间未发现具有统计学意义的差异。结果发现,实验组乳牙列的龋齿发病率增长显著低于对照组(def-t分别为0.61和1.07),而第一恒磨牙的龋齿发病率增长差异不显著(两组DMF-T均为1.62)。据估计,其效果归因于局部作用的氟化物对正在萌出的乳牙列具有长期防龋作用,而恒牙列(第一恒磨牙)在研究开始时已完成牙冠钙化,但尚未萌出。据估计,在该研究组较晚萌出的牙齿中,防龋效果最为明显。

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