Ezeofor S N, Obikili E N, Anyanwu G E, Onuh A C, Mgbor S O
Department of Radiation Medicine, College of Medicine, Faculty of Medical Sciences, University of Nigeria, Enugu Campus, Enugu State, Nigeria.
Niger J Clin Pract. 2014 Jul-Aug;17(4):484-8. doi: 10.4103/1119-3077.134046.
BACKGROUND/OBJECTIVE: Ultrasonogrphy is a good modality for the detection of splenomegaly even when it is not clinically palpable. The objective of this study was to establish the normal values of splenic length in healthy school children in South-East, Nigeria and to correlate them with body indices.
This is a cross-sectional prospective study of 1315 children (633 boys and 682 girls) between the ages of 5 and 17 years. The splenic length was measured between the most superiomedial and the most inferiolateral margins, at the level of the hilum. Only the spleens that had normal shape and echotexture were measured. The mean splenic length and the 5 th and 95 th percentiles were determined for each age. The length was correlated with the sex, age, weight (WT), height, body mass index (BMI) and body surface area (BSA) of the subjects. A regression model for prediction of spleen dimension from age and body habitus was computed.
There was a significant correlation between splenic length and age, P < 0.001. Males had statistically significant longer spleen length than females. The splenic length correlated best with BSA, followed by body WT and least with BMI.
This study noted racial variation between the established Nigerian values and results from other countries of the world. For the first time, a baseline value for splenic size for the Nigerian Children of various ages has been established with a regression model for predicting the splenic sizes.
背景/目的:超声检查是检测脾肿大的一种良好方法,即使在临床上无法触及脾脏时也能检测到。本研究的目的是确定尼日利亚东南部健康学龄儿童脾脏长度的正常值,并将其与身体指标相关联。
这是一项对1315名年龄在5至17岁之间的儿童(633名男孩和682名女孩)进行的横断面前瞻性研究。在脾门水平测量脾脏最上内侧和最下外侧边缘之间的长度。仅测量形状和回声纹理正常的脾脏。确定每个年龄组的平均脾脏长度以及第5和第95百分位数。将脾脏长度与受试者的性别、年龄、体重(WT)、身高、体重指数(BMI)和体表面积(BSA)相关联。计算了一个根据年龄和身体状况预测脾脏大小的回归模型。
脾脏长度与年龄之间存在显著相关性,P < 0.001。男性的脾脏长度在统计学上显著长于女性。脾脏长度与BSA的相关性最好,其次是体重,与BMI的相关性最小。
本研究指出尼日利亚既定值与世界其他国家的结果之间存在种族差异。首次为尼日利亚不同年龄段的儿童建立了脾脏大小的基线值,并建立了一个预测脾脏大小的回归模型。