Matzumura-Kuan Melissa, Jennings Jeffrey
From the Department of Internal Medicine.
Scand J Infect Dis. 2014 Sep;46(9):669-72. doi: 10.3109/00365548.2014.920104. Epub 2014 Jun 9.
Pulmonary infections can mimic a pulmonary neoplasm. Multiple organisms, including bacteria, viruses, and fungi, can present with similar clinical, radiographic, and surgical findings as neoplastic processes. Because treatment and the prognosis are completely different, an accurate diagnosis is crucial, and lung biopsy is usually required. Aggregatibacter actinomycetemcomitans is part of the normal oral flora and is a rare cause of invasive infection due to hematogenous dissemination or aspiration, particularly infective endocarditis. We present a case of A. actinomycetemcomitans and Actinomyces co-infection that presented as a mediastinal mass, with surgical findings similar to lung malignancy but with biopsy and culture showing an infectious origin. After antibiotic treatment, follow-up images showed resolution of the mass.
肺部感染可能会与肺部肿瘤相似。多种病原体，包括细菌、病毒和真菌，可能呈现出与肿瘤性病变相似的临床、影像学和手术表现。由于治疗方法和预后完全不同，准确的诊断至关重要，通常需要进行肺活检。伴放线聚集杆菌是正常口腔菌群的一部分，是血行播散或误吸导致侵袭性感染的罕见原因，尤其是感染性心内膜炎。我们报告一例伴放线聚集杆菌与放线菌合并感染的病例，该病例表现为纵隔肿块，手术所见与肺恶性肿瘤相似，但活检和培养显示为感染性病因。抗生素治疗后，随访影像显示肿块消退。
