Belcher Britni R, Moser Richard P, Dodd Kevin W, Atienza Audie A, Ballard-Barbash Rachel, Berrigan David
Cancer Prevention Fellowship Program, Division of Cancer Prevention, Health Behaviors Research Branch, Behavioral Research Program, National Cancer Institute, Bethesda, MD.
J Phys Act Health. 2015 May;12(5):708-16. doi: 10.1123/jpah.2013-0193. Epub 2014 Jun 4.
Discrepancies in self-report and accelerometer-measured moderate-to-vigorous physical activity (MVPA) may influence relationships with obesity-related biomarkers in youth.
Data came from 2003-2006 National Health and Nutrition Examination Surveys (NHANES) for 2174 youth ages 12 to 19. Biomarkers were: body mass index (BMI, kg/m2), BMI percentile, height and waist circumference (WC, cm), triceps and subscapular skinfolds (mm), systolic & diastolic blood pressure (BP, mmHg), high-density lipoprotein (HDL, mg/dL), total cholesterol (mg/dL), triglycerides (mg/dL), insulin (μU/ml), C-reactive protein (mg/dL), and glycohemoglobin (%). In separate sex-stratified models, each biomarker was regressed on accelerometer variables [mean MVPA (min/day), nonsedentary counts, and MVPA bouts (mean min/day)] and self-reported MVPA. Covariates were age, race/ethnicity, SES, physical limitations, and asthma.
In boys, correlations between self-report and accelerometer MVPA were stronger (boys: r = 0.14-0.21; girls: r = 0.07-0.11; P < .010) and there were significant associations with BMI, WC, triceps skinfold, and SBP and accelerometer MVPA (P < .01). In girls, there were no significant associations between biomarkers and any measures of physical activity.
Physical activity measures should be selected based on the outcome of interest and study population; however, associations between PA and these biomarkers appear to be weak regardless of the measure used.
自我报告的中度至剧烈身体活动（MVPA）与通过加速度计测量的结果之间存在差异，这可能会影响青少年与肥胖相关生物标志物之间的关系。
数据来自2003 - 2006年全国健康与营养检查调查（NHANES），涉及2174名12至19岁的青少年。生物标志物包括：体重指数（BMI，kg/m²）、BMI百分位数、身高和腰围（WC，cm）、肱三头肌和肩胛下皮褶厚度（mm）、收缩压和舒张压（BP，mmHg）、高密度脂蛋白（HDL，mg/dL）、总胆固醇（mg/dL）、甘油三酯（mg/dL）、胰岛素（μU/ml）、C反应蛋白（mg/dL）和糖化血红蛋白（%）。在按性别分层的独立模型中，每个生物标志物都与加速度计变量[平均MVPA（分钟/天）、非久坐计数和MVPA发作次数（平均分钟/天）]以及自我报告的MVPA进行回归分析。协变量包括年龄、种族/民族、社会经济地位、身体限制和哮喘。
在男孩中，自我报告的MVPA与加速度计测量的MVPA之间的相关性更强（男孩：r = 0.14 - 0.21；女孩：r = 0.07 - 0.11；P <.010），并且BMI、WC、肱三头肌皮褶厚度和收缩压与加速度计测量的MVPA之间存在显著关联（P <.01）。在女孩中，生物标志物与任何身体活动指标之间均无显著关联。
应根据感兴趣的结果和研究人群选择身体活动测量方法；然而，无论使用何种测量方法，身体活动与这些生物标志物之间的关联似乎都很弱。
