Hétet J-F, Colls P, Pocholle P, Chauveau P, Barré C, Hallouin P
Service de chirurgie urologique, clinique Jules-Verne, 2-4, route de Paris, 44314 Nantes cedex 3, France.
Service de chirurgie urologique, clinique Jules-Verne, 2-4, route de Paris, 44314 Nantes cedex 3, France.
Cancer Radiother. 2014 Nov;18(7):701-8. doi: 10.1016/j.canrad.2014.04.002. Epub 2014 Jun 6.
Potentially curative salvage options for biochemical failure after primary prostatic radiotherapy include salvage radical prostatectomy, brachytherapy, high-intensity focused ultrasound and cryotherapy. Salvage cryoablation for recurrent prostate cancer after irradiation failure is currently a well-established therapeutic option, since technical improvements have permitted better oncologic outcomes and lower complications rates over the years. This article reviews surgical technique, oncologic and functional outcomes, as well as morbidity and complications of salvage cryotherapy for local recurrence after external beam radiotherapy or brachytherapy for prostate cancer.
前列腺癌初次放疗后生化复发的潜在治愈性挽救治疗方案包括挽救性根治性前列腺切除术、近距离放射治疗、高强度聚焦超声和冷冻治疗。放射治疗失败后复发性前列腺癌的挽救性冷冻消融目前是一种成熟的治疗选择，因为多年来技术改进已带来更好的肿瘤学结果和更低的并发症发生率。本文综述了前列腺癌外照射放疗或近距离放射治疗后局部复发的挽救性冷冻治疗的手术技术、肿瘤学和功能结果，以及发病率和并发症。
