Asin Ungria J, Pina Salvador J M, Beltrán Audera J, Otero Escalante W, Cía Gómez P
An Med Interna. 1989 Jan;6(1):33-5.
The incidence of rheumatoid valvular disease is among 2.5% to 30% of necropsy patients with rheumatoid arthritis. The valves may be affected by a granulomatous form patognomonic, or by unspecific inflammatory changes (the most frequent 90-99%). We present a patient affected by a classical seropositive rheumatoid arthritis accompanied by mixed stenosis and incompetence of both mitral and aortic valves. The patient underwent replacement of both valves, and typical unspecific inflammatory changes were detected histologically in the valvular tissues. Replacement of the valves by a prosthesis is the choice treatment despite severe joint disease. The echocardiography is the ideal method for detection of cases with subclinic lesions and to continue evolution.
类风湿性瓣膜病在类风湿性关节炎尸检患者中的发生率为2.5%至30%。瓣膜可能受到肉芽肿性特征性形式的影响，或受到非特异性炎症变化的影响（最常见的为90% - 99%）。我们报告一例患有典型血清阳性类风湿性关节炎的患者，同时伴有二尖瓣和主动脉瓣混合性狭窄及关闭不全。该患者接受了双瓣膜置换，组织学检查在瓣膜组织中发现了典型的非特异性炎症变化。尽管存在严重的关节疾病，但采用人工瓣膜置换仍是首选治疗方法。超声心动图是检测亚临床病变病例并持续监测病情进展的理想方法。
