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近期肺动脉支架:即刻及中期随访

Pulmonary artery stents in the recent era: Immediate and intermediate follow-up.

作者信息

Ing Frank F, Khan Asra, Kobayashi Daisuke, Hagler Donald J, Forbes Thomas J

机构信息

Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, California.

出版信息

Catheter Cardiovasc Interv. 2014 Dec 1;84(7):1123-30. doi: 10.1002/ccd.25567. Epub 2014 Jul 2.

Abstract

BACKGROUND

Long-term follow-up after stent dilation of native and acquired pulmonary artery stenosis is scarce in the pediatric population. Most cohorts include a myriad of anatomies and associated conditions.

METHOD

In order to establish objective performance criteria, we performed a retrospective review of all patients who underwent unilateral pulmonary artery stenting in biventricular physiology at three centers from June 2006 to June 2011.

RESULTS

Fifty-eight patients received 60 stents with Palmaz Genesis stent used most commonly (78%). Average age at implantation was 10.4 ± 10.3 years and weight 31.6 ± 21.8 kg. The immediate success rate was 98%, with improvement in minimal diameter from 5.1 ± 2 cm to 10.6 ± 3 cm (P < 0.01). There were 10 complications (7 major and 3 minor) and no acute mortality. One-year follow-up studies were available in 48 patients (83%), including echocardiogram (60%), catheterization (28%), MRI (29%), and lung perfusion (31%). Follow-up echocardiogram showed mild increase in stent gradient, from 5.7 ± 6.7 mm Hg post-procedure to 17.1 ± 11.7 mm Hg. Follow-up catheterization showed no significant change in minimal stent diameter (8.8 ± 2.6 to 7.8 ± 2.3 mm), gradient (7.7 ± 8.4 to 12.6 ± 12.2 mm Hg), or right ventricular pressures (43.7 ± 9 to 47.7 ± 10.5 mm Hg). Nine patients (16%) underwent scheduled stent redilation over a period of 12 days to 25 months.

CONCLUSION

In conclusion, stent implantation shows excellent immediate and 1-year follow-up results with maintenance of improved caliber of the stented vessel and lowered right ventricular systolic pressures.

摘要

背景

在儿科人群中,对原发性和后天性肺动脉狭窄进行支架扩张术后的长期随访资料较少。大多数队列研究包含了各种各样的解剖结构和相关病症。

方法

为了建立客观的性能标准,我们对2006年6月至2011年6月期间在三个中心接受双心室生理状态下单侧肺动脉支架置入术的所有患者进行了回顾性研究。

结果

58例患者接受了60枚支架,最常用的是Palmaz Genesis支架(78%)。植入时的平均年龄为10.4±10.3岁,体重为31.6±21.8千克。即刻成功率为98%,最小直径从5.1±2厘米增加到10.6±3厘米(P<0.01)。发生了10例并发症(7例严重,3例轻微),无急性死亡病例。48例患者(83%)进行了为期一年的随访研究,包括超声心动图(60%)、心导管检查(28%)、磁共振成像(29%)和肺灌注(31%)。随访超声心动图显示支架压力阶差轻度增加,从术后的5.7±6.7毫米汞柱增至17.1±11.7毫米汞柱。随访心导管检查显示支架最小直径(8.8±2.6至7.8±2.3毫米)、压力阶差(7.7±8.4至12.6±12.2毫米汞柱)或右心室压力(43.7±9至47.7±10.5毫米汞柱)无显著变化。9例患者(16%)在12天至25个月的时间内接受了计划性支架再扩张术。

结论

总之,支架植入术显示出优异的即刻和一年随访结果,能维持支架置入血管的管径改善并降低右心室收缩压。

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