Zhou X F, Zhou Q
Agricultural Antibiotic Laboratory, Huazhong Agricultural University, Wuhan.
Chin J Biotechnol. 1989;5(3):161-6.
The frequency of recombination between Streptomyces hygroscopicus var. yingchengensis and Streptomyces qingfengmyceticus as a result of interspecific protoplast fusion was 4.5 x 10(-4). Characterization of biological properties revealed differences in spore mass color, drug resistance, antimicrobial activity, and antibiotic production capacity between the recombinants and their parents. Two recombinant strains, FL-42 and FL-48, exhibited production of the antibiotics originally elaborated by the two parents individually. They also produced two compounds with antimicrobial activity that their parents could not synthesize.
吸水链霉菌应城变种与庆丰链霉菌间原生质体融合产生的重组频率为4.5×10⁻⁴。生物学特性表征显示,重组体与其亲本在孢子堆颜色、耐药性、抗菌活性及抗生素生产能力方面存在差异。两个重组菌株FL - 42和FL - 48分别产生了最初由两个亲本各自合成的抗生素。它们还产生了两种具有抗菌活性的化合物,而其亲本无法合成这些化合物。