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[塞内加尔多发性神经炎的病因学方面]

[Etiological aspects of polyneuritis in Senegal].

作者信息

Ndiaye I P, Ndiaye M M, Mauferon J B, Diagne M, Diop A G

机构信息

Clinique Neurologique du C.H.U. Fann, Dakar.

出版信息

Dakar Med. 1989;34(1-4):68-71.

PMID:2491390
Abstract

This study of 115 cases documented by the Neurology Unit between 1970 and 1984, stresses the relative frequency of deficiency etiology. The study was conducted clinically, biologically and electrophysiologically. Distribution between the sexes is almost equal, and the main age group concerned, those between 20 and 40 years. The various ethnic groups are all similarly affected. "Tropical Neuropathies" (most frequently of deficiency origin) are very important and account for half the cases. They are followed, in decreasing order of frequency, by toxic polyneuritis (ethanol and INH), degenerative polyneuritis with Charcot Marie-Tooth's sickness leading, and finally metabolic polyneuritis-diabetic (but diabetes creates no more polyneuritis than multineuritis) and uremic. The frequency of polyneuritis is the same as in European statistics. "Tropical Neuropathy" is a vast, ill defined subject which has been made to include many polyneurites which, in the end after a number of years, turned out to be degenerative polyneuritis. The result of this study will probably be to erode the classification "Tropical Neuropathy", which already displays inexactitudes in long term studies because of the discovery of a significant number of degenerative etiologies wrongly included in the past.

摘要

这项对神经科在1970年至1984年间记录的115例病例的研究,强调了营养缺乏病因的相对发生率。该研究通过临床、生物学和电生理学方法进行。两性之间的分布几乎相等,主要涉及的年龄组为20至40岁。各个种族受影响程度相似。“热带神经病”(最常见的是营养缺乏所致)非常重要,占病例的一半。其次,按频率递减顺序依次为中毒性多发性神经炎(乙醇和异烟肼所致)、以夏科-马里-图斯病为主的变性性多发性神经炎,最后是代谢性多发性神经炎——糖尿病性(但糖尿病引起的多发性神经炎并不比多神经炎更多)和尿毒症性。多发性神经炎的发生率与欧洲统计数据相同。“热带神经病”是一个宽泛且定义不明确的主题,其中包含了许多多发性神经炎病例,最终经过数年发现,其中许多原来是变性性多发性神经炎。这项研究的结果可能会削弱“热带神经病”这一分类,由于发现过去错误纳入了大量变性病因,该分类在长期研究中已显示出不准确之处。

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