Lau Henry H W, Yip Wilson W K, Lee Allie, Lai Connie, Fan Dorothy S P
Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin, Hong Kong.
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Hong Kong.
Hong Kong Med J. 2014 Jun;20(3):261-3. doi: 10.12809/hkmj134059.
Three cases of juvenile xanthogranuloma from two ophthalmology departments were reviewed. Clinical histories, ophthalmic examination, physical examination, investigations, and treatment of these cases are described. A 4-month-old boy presented with spontaneous hyphema and secondary glaucoma. He was treated with intensive topical steroid and anti-glaucomatous eye drops. The hyphema gradually resolved and the intra-ocular pressure reverted to 11 mm Hg without any other medication. Biopsy of his scalp mass confirmed the diagnosis of juvenile xanthogranuloma. A 31-month-old boy presented with a limbal mass. Excisional biopsy of the mass was performed and confirmed it was a juvenile xanthogranuloma. A 20-month-old boy was regularly followed up for epiblepharon and astigmatism. He presented to a paediatrician with a skin nodule over his back. Skin biopsy confirmed juvenile xanthogranuloma. He had no other ocular signs. Presentation of juvenile xanthogranuloma can be very different, about which ophthalmologists should be aware of. Biopsy of the suspected lesion is essential to confirm the diagnosis.
回顾了来自两个眼科科室的3例幼年性黄色肉芽肿病例。描述了这些病例的临床病史、眼科检查、体格检查、检查及治疗情况。一名4个月大的男婴出现自发性前房积血和继发性青光眼。他接受了强化局部类固醇和抗青光眼眼药水治疗。前房积血逐渐消退，眼压恢复到11毫米汞柱，无需其他药物治疗。对其头皮肿块进行活检，确诊为幼年性黄色肉芽肿。一名31个月大的男婴出现角膜缘肿块。对该肿块进行切除活检，证实为幼年性黄色肉芽肿。一名20个月大的男婴因睑缘赘皮和散光接受定期随访。他因背部皮肤结节就诊于儿科医生。皮肤活检确诊为幼年性黄色肉芽肿。他没有其他眼部体征。幼年性黄色肉芽肿的表现可能非常不同，眼科医生应予以关注。对疑似病变进行活检对于确诊至关重要。
