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[急性早幼粒细胞白血病患者接受强化化疗后无骨髓再生障碍期的完全缓解]

[Complete remission without marrow aplasia phase in a patient with acute promyelocytic leukosis treated with aggressive chemotherapy].

作者信息

del Potro Gómez E, Martínez Martínez R, López Martín J C, Díaz Morfa M, Díaz Mediavilla J, Espinos Pérez D

出版信息

An Med Interna. 1989 May;6(5):255-6.

PMID:2491539
Abstract

A patient diagnose of acute promyelocytic leukemia treated with chemotherapy schedule type VAPA. 2 weeks after the administration, there was no response this being the reason to administer a new induction course. 2 weeks after this, a new bone marrow aspiration was performed showing leukemic infiltration with 78% promyelocytes. The clinical situation of the patient did not recommend the addition of more chemotherapy. 10 days later complete remission in bone marrow and blood were demonstrated. The importance of this finding is discussed, complete remission without aplasia, as well as the diagnosis and therapeutic remarks of the case.

摘要

一名被诊断为急性早幼粒细胞白血病的患者接受了VAPA化疗方案治疗。给药2周后,没有反应,这成为进行新的诱导疗程的原因。在此之后2周,进行了一次新的骨髓穿刺,显示有白血病浸润,早幼粒细胞占78%。患者的临床情况不建议增加更多化疗。10天后,骨髓和血液显示完全缓解。讨论了这一发现的重要性,即无再生障碍的完全缓解,以及该病例的诊断和治疗要点。

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