Perren Fabienne, Magistris Michel R
Division of Neurology, Department of Clinical Neurosciences, HUG, University Hospital and Medical Faculty of Geneva, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 14, Switzerland,
Acta Neurochir (Wien). 2014 Aug;156(8):1557-60. doi: 10.1007/s00701-014-2132-7. Epub 2014 Jun 12.
Arterial tortuosity of the posterior circulation compressing the facial nerve induces the ephaptic axono-axonal cross-talk that sparks hemifacial spasm. We sought if a noninvasive method such as color duplex of these arteries might detect hemodynamical changes in this condition.
Nine patients with hemifacial spasm, successfully treated with botulinum toxin, were examined with color-coded duplex ultrasound. Mean blood flow velocities of the vertebral, basilar, posterior inferior cerebellar, and anterior inferior cerebellar arteries were measured and side-to-side comparison performed.
In all nine patients, the mean blood flow velocity, averaging across the two arteries, was higher on the side of the hemifacial spasm (Fisher's exact p < 0.008; two-tailed). The results of the repeated measures ANOVA show that the main effect of side of flow was statistically significant, F(1,8) = 17.354, p = .0032, with higher mean blood flow velocities observed on the side of the hemifacial spasm. There was no significant association between the mean flow velocity of the vertebral artery and the side of spasm (p = 0.523).
Hemifacial spasm also seems to relate to hemodynamic changes, which may be detectable by color duplex imaging.
后循环动脉迂曲压迫面神经会引发引发半面痉挛的电突触轴突-轴突串扰。我们探究像这些动脉的彩色双功超声这样的非侵入性方法是否能检测出这种情况下的血流动力学变化。
对9例经肉毒杆菌毒素成功治疗的半面痉挛患者进行彩色编码双功超声检查。测量椎动脉、基底动脉、小脑后下动脉和小脑前下动脉的平均血流速度，并进行双侧比较。
在所有9例患者中，两侧动脉平均血流速度在半面痉挛侧更高（Fisher精确检验p < 0.008；双侧）。重复测量方差分析结果显示，血流侧的主效应具有统计学意义，F(1,8) = 17.354，p = 0.0032，半面痉挛侧的平均血流速度更高。椎动脉平均流速与痉挛侧之间无显著相关性（p = 0.523）。
半面痉挛似乎也与血流动力学变化有关，彩色双功成像可能检测到这些变化。
